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Evidence from auditory nerve and brainstem evoked responses for an organic brain lesion in children with autistic traits

  • M. Student
  • H. Sohmer
Articles

Abstract

In an attempt to resolve the question as to whether children with autistic traits have an organic nervous system lesion, auditory nerve and brainstem evoked responses were recorded in a group of 15 children with autistic traits. The most obvious results included a longer response latency of the auditory nerve and a longer brainstem transmission time, compared to normal children. Five of the autistic children were found to be profoundly deaf. These results strengthen the theory that an organic lesion of the nervous system can give rise to autistic traits.

Keywords

Nervous System Response Latency Brain Lesion Transmission Time Normal Child 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Creak, E. M. Childhood psychosis: A review of 100 cases.British Journal of Psychiatry, 1963,109, 84–89.PubMedGoogle Scholar
  2. Goff, W. R., Allison, T., Lyons, W., Fisher, T. C., & Conte, R. Origin of short latency auditory evoked response components in man. In J. E. Desmedt (Ed.),Cerebral evoked potentials in man. In press.Google Scholar
  3. Hecox, K., & Galambos, R. Brainstem auditory evoked responses in human infants and adults.Archives of Otolaryngology, 1974,99, 30–33.PubMedGoogle Scholar
  4. Kanner, L. Autistic disturbances of affective contact.Nervous Child, 1943,2, 217–250.Google Scholar
  5. Kanner, L. Problems of nosology and psychodynamics of early infantile autism.American Journal of Orthopsychiatry, 1949,19, 416–452.Google Scholar
  6. Lev, A., & Sohmer, H. Sources of averaged neural responses recorded in animal and human subjects during cochlear audiometry (electrocochleogram).Archiv für Klinische und Experimentelle Ohren-, Nasen- und Kehlkopfheilkunde, 1972,201, 79–90.Google Scholar
  7. Lieberman, A., Sohmer, H., & Szabo, G. Standard values of amplitude and latency of cochlear audiometry (electro-cochleography) responses in different age groups.Archiv für Klinische und Experimentelle Ohren-, Nasen- und Kehlkopfheilkunde, 1973,203, 267–273.Google Scholar
  8. Makita, K. Contemporary concept of autism and autismus infantum.Acta Paedopsychiatrica, 1974,41, 162–168.Google Scholar
  9. Ornitz, E. M., & Ritvo, E. R. Neurophysiologic mechanisms underlying perceptual inconstancy in autistic and schizophrenic children.Archives of General Psychiatry, 1968,19, 22–27.PubMedGoogle Scholar
  10. Ornitz, E. M., & Ritvo, E. R. The syndrome of autism: Critical review.American Journal of Psychiatry, 1976,133, 609–621.PubMedGoogle Scholar
  11. Ornitz, E. M., Ritvo, E. R., Panman, L. M., Lee, Y. H., Carr, E. M., & Walter, R. D. The auditory evoked responses in normal and autistic children during sleep.Electroencephalography and Clinical Neurophysiology, 1968,25, 221–230.PubMedGoogle Scholar
  12. Picton, T. W., Woods, D. L., Baribeau-Braun, J., and Healey, T. M. G. Evoked potential audiometry.Journal of Otolaryngology, 1977,6, 90–119.Google Scholar
  13. Piggott, L., Ax, A. F., Bamford, J. L., & Fetzner, J. M. Respiration sinus arrhythmia in psychotic children.Psychophysiology, 1973,10, 401–414.PubMedGoogle Scholar
  14. Pratt, H., & Sohmer, H. Intensity and rate functions of cochlear and brainstem evoked responses to click stimuli in man.Archives of Oto-Rhino-Laryngology, 1976,212, 85–92.PubMedGoogle Scholar
  15. Ritvo, E. R., Ornitz, E. M., Eviatar, A., Markham, C. H., Brown, M. B., & Mason, A. Decreased postrotatory nystagmus in early infantile autism.Neurology, 1969,19, 653–658.PubMedGoogle Scholar
  16. Rutter, M., & Bartak, L. Causes of infantile autism: Some considerations from recent research.Journal of Autism and Childhood Schizophrenia, 1971,1, 20–32.PubMedGoogle Scholar
  17. Salamy, A., McKean, C. M., & Buda, F. B. Maturational changes in auditory transmission as reflected in human brainstem potentials.Brain Research, 1975,96, 361–366.PubMedGoogle Scholar
  18. Schopler, E. Early infantile autism and receptor processes.Archives of General Psychiatry, 1965,13, 327–335.PubMedGoogle Scholar
  19. Sohmer, H., & Cohen, D. Responses of the auditory pathway in several types of hearing loss. In R. J. Ruben, C. Elberling, & G. Salomon (Eds.),Electrocochleography. Baltimore: University Park Press, 1976.Google Scholar
  20. Sohmer, H., & Feinmesser, M. Routine use of electro-cochleography (cochlear audiometry) on human subjects.Audiology, 1973,12, 167–173.PubMedGoogle Scholar
  21. Sohmer, H., Feinmesser, M., & Szabo, G. Electrocochleographic (auditory nerve and brainstem auditory nuclei) responses to sound stimuli in patients with brain damage.Electroencephalography and Clinical Neurophysiology, 1973,34, 761.Google Scholar
  22. Sohmer, H., Feinmesser, M., & Szabo, G. Sources of electrocochleographic responses as studied in patients with brain damage.Electroencephalography and Clinical Neurophysiology, 1974,37, 663–669.PubMedGoogle Scholar
  23. Sohmer, H., Pratt, H., & Feinmesser, M. Electrocochleography or evoked cortical responses: Which is preferable in diagnosis of hearing loss?Revue de Laryngologie Otologie-Rhinologie, 1974,95, 515–522.PubMedGoogle Scholar
  24. Starr, A., & Achor, J. Auditory brainstem responses in neurological disease.Archives of Neurology, 1975,32, 761–768.PubMedGoogle Scholar
  25. Starr, A., & Hamilton, A. Correlation between confirmed sites of neurological lesions and abnormalities of the far field auditory brainstem responses.Electroencephalography and Clinical Neurophysiology, 1976,41, 595–608.PubMedGoogle Scholar
  26. Student, M.Electrocochleographic tests on children with autistic traits. Unpublished Master's thesis, University of Tel Aviv, 1975.Google Scholar
  27. Tanguay, P. E., Ornitz, E. M., Forsythe, A. B., & Ritvo, E. R. Rapid eye movement (REM) activity in normal and autistic children during REM sleep.Journal of Autism and Childhood Schizophrenia, 1976,6, 275–288.PubMedGoogle Scholar
  28. Terkildsen, K., Osterhammel, P., & Huis in't Veld, F. Electrocochleography with far field technique.Scandinavian Audiology, 1973,2, 141–148.Google Scholar
  29. Thornton, A. R. D. Statistical properties of surface-recorded electrocochleographic responses.Scandinavian Audiology, 1975,4, 91–102.Google Scholar

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • M. Student
    • 1
  • H. Sohmer
    • 2
  1. 1.Department of Behavioral SciencesTel Aviv UniversityTel Aviv
  2. 2.Department of PhysiologyHebrew University-Hadassah Medical SchoolJerusalemIsrael

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