Somatic Cell and Molecular Genetics

, Volume 12, Issue 5, pp 513–517 | Cite as

Chromosomal localization of human gene for histidyl-tRNA synthetase: Clustering of genes encoding aminoacyl-tRNA synthetases on human chromosome 5

  • John J. Wasmuth
  • Leon R. Carlock
Brief Communication
Received:
Revised:

Abstract

The gene encoding histidyl-tRNA synthetase was localized to human chromosome 5 using human-Chinese hamster ovary cell hybrids. Seven of the functionally related genes encoding the 20 different aminoacyl-tRNA synthetases have now been mapped in humans and four are located on a single chromosome, number 5, which represents less than 7 % of the total genome. Thus, there appears to be significant clustering of this group of genes which may reflect their evolutionary relatedness or common factors involved in regulating their expression.

Keywords

Related Gene Human Gene Common Factor Human Chromosome Chromosomal Localization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • John J. Wasmuth
    • 1
  • Leon R. Carlock
    • 1
  1. 1.Department of Biological Chemistry, California College of MedicineUniversity of CaliforniaIrvine

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