Autism and autoimmune disease: A family study
- 201 Downloads
A family is presented to demonstrate the rare phenomenon of early infantile autism in the presence of autoimmune disease. The youngest son in the family has a multiple diagnosis of autism, Addison's disease, and moniliasis. The next older brother has hypoparathyroidism, Addison's disease, moniliasis, and diabetes mellitus. The next older brother has hypoparathyroidism, Addison's disease, moniliasis, and alopecia totalis. The oldest son and first born child in this family of four is, along with the parents, symptom free. Whereas autism in the youngest son might be attributed to the traumatic family situation, in which there exists the constant threat of near-death, it might conceivably be attributed also to a primary effect of autoimmune impairment from the formation of autoantibodies affecting the central nervous system.
Unable to display preview. Download preview PDF.
- Bettelheim, B.The empty fortress: Infantile autism and the birth of the self. New York: Free Press, 1967.Google Scholar
- Burnet, F. M.Self and not self: Cellular immunology. Vol. 1. London: Cambridge University Press, 1969.Google Scholar
- Cohen, J. The factorial structure of the WISC at ages 7-6, 10-6, and 13-6.Journal of Consulting Psychology, 1959,23, 285–299.Google Scholar
- Dohan, F. C. Schizophrenia: Possible relationship to cereal grains and celiac disease. In S. Sankar (Ed.),Schizophrenia: Current concepts and research. Hicksville, N.Y.: P.J.D. Publications, 1969. Pp. 539–551. (b)Google Scholar
- Kanner, L. Autistic disturbances of affective contact.Nervous Child, 1943,2, 217–250.Google Scholar
- Kanner, L. Early infantile autism.Journal of Pediatrics, 1944,25, 211–217.Google Scholar
- Kanner, L. Problems of nosology and psychodynamics of early infantile autism.American Journal of Orthopsychiatry, 1949,19, 416–426.Google Scholar
- Ogdon, D. P., Bass, C. L., Thomas, E. R., & Lordi, W. Parents of autistic children.American Journal of Orthopsy chiatry, 1968,38, 653–658.Google Scholar
- Pasamanick, B., & Knobloch, H. Epidemiologic studies on the complications of pregnancy and the birth process. In G. Caplan (Ed.),Prevention of mental disorders in childhood. New York: Basic Books, 1961. Pp. 74–94.Google Scholar
- Rimland, B.Infantile autism. New York: Appleton-Century-Crofts, 1964.Google Scholar
- Ross, I. S. An autistic child.Pediatric Conferences (Babies Hospital Unit, United Hospitals of Newark, New Jersey), 1959,2, 1–13.Google Scholar