Somatic Cell and Molecular Genetics

, Volume 14, Issue 1, pp 93–98

Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively

  • George L. Long
  • Angus Marshall
  • Julia C. Gardner
  • Susan L. Naylor
Brief Communication

DOI: 10.1007/BF01535052

Cite this article as:
Long, G.L., Marshall, A., Gardner, J.C. et al. Somat Cell Mol Genet (1988) 14: 93. doi:10.1007/BF01535052

Abstract

cDNAs encoding human proteins C and S have been used to screen a panel of mouse-human somatic cell hybrids to determine the chromosomal location of their respective genes. The gene for human protein C is located on chromosome 2, whereas that for protein S is located on chromosome 3. Analysis of human genomic DNA restriction endonuclease fragmentation patterns suggests that the human protein S gene is greater than 40 kb in size and contains a minimum of 11 introns.

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • George L. Long
    • 1
  • Angus Marshall
    • 2
  • Julia C. Gardner
    • 2
  • Susan L. Naylor
    • 2
  1. 1.Department of Biochemistry, College of MedicineUniversity of VermontBurlington
  2. 2.Department of Cellular and Structural BiologyThe University of Texas Health Science Center at San AntonioSan Antonio

Personalised recommendations