Somatic Cell and Molecular Genetics

, Volume 14, Issue 1, pp 93–98 | Cite as

Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively

  • George L. Long
  • Angus Marshall
  • Julia C. Gardner
  • Susan L. Naylor
Brief Communication


cDNAs encoding human proteins C and S have been used to screen a panel of mouse-human somatic cell hybrids to determine the chromosomal location of their respective genes. The gene for human protein C is located on chromosome 2, whereas that for protein S is located on chromosome 3. Analysis of human genomic DNA restriction endonuclease fragmentation patterns suggests that the human protein S gene is greater than 40 kb in size and contains a minimum of 11 introns.


Restriction Endonuclease Somatic Cell Plasma Protein Chromosomal Location Human Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • George L. Long
    • 1
  • Angus Marshall
    • 2
  • Julia C. Gardner
    • 2
  • Susan L. Naylor
    • 2
  1. 1.Department of Biochemistry, College of MedicineUniversity of VermontBurlington
  2. 2.Department of Cellular and Structural BiologyThe University of Texas Health Science Center at San AntonioSan Antonio

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