Somatic Cell and Molecular Genetics

, Volume 14, Issue 2, pp 217–221 | Cite as

Structural gene encoding human factor XII is located at 5q33-qter

  • N. J. Royle
  • M. Nigli
  • D. Cool
  • R. T. MacGillivray
  • J. L. Hamerton
Brief Communication


The gene encoding human factor XII (F12 ) or Hageman factor has been mapped to 5q33-qter. This has been achieved by analyzing the results obtained from hybridizing a cloned fragment from the factor XII gene to a panel of human-hamster somatic cell hybrid DNAs and also by in situ hybridization to normal human metaphase cells. The previously reported results localizingF12 to 6p23 are discussed.


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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • N. J. Royle
    • 1
  • M. Nigli
    • 1
  • D. Cool
    • 2
  • R. T. MacGillivray
    • 2
  • J. L. Hamerton
    • 1
  1. 1.Department of Human GeneticsUniversity of ManitobaCanada
  2. 2.Department of BiochemistryUniversity of British ColumbiaCanada

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