Acta Neurochirurgica

, Volume 42, Issue 1–2, pp 123–125 | Cite as

The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium

  • F. Heppner
  • J. R. Möse


Vascular glioblastomas become liquefied when contaminated with spores of the non-pathogenic Clostridium butyricum M 55. The spores are administered by intracarotid injection. The oncolysis is complete one week after injection. The glioblastoma is converted into a brain abscess which is then operated on appropriately. Forty nine patients have been treated in this manner. The rate of recurrence, however, remained uninfluenced.


Public Health Interventional Radiology Liquefaction Invasive Surgery Clostridium 
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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • F. Heppner
    • 1
  • J. R. Möse
    • 1
  1. 1.Neurosurgical DepartmentUniversity of GrazGrazAustria

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