Acta Neurochirurgica

, Volume 68, Issue 3–4, pp 239–251 | Cite as

The effect of systemic human interferon-alpha administration to patients with glioblastoma multiforme

  • J. Boëthius
  • H. Blomgren
  • V. P. Collins
  • T. Greitz
  • H. Strander


This report presents the results of a phase I trial of the value of human leucocyte inferon-alpha in the treatment of glioblastoma. Twelve patients entered the trial. In one case we believe that the patient benefitted from the interferon treatment. CT scans of patients on interferon did not reveal the true extent of the tumorous tissue.


Glioblastoma multiforme human interferon 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • J. Boëthius
    • 1
  • H. Blomgren
    • 2
  • V. P. Collins
    • 3
  • T. Greitz
    • 4
  • H. Strander
    • 2
  1. 1.Department of NeurosurgeryKarolinska HospitalStockholmSweden
  2. 2.Department of RadiumhemmetKarolinska HospitalStockholmSweden
  3. 3.Department of Tumour PathologyKarolinska HospitalStockholmSweden
  4. 4.Department of NeuroradiologyKarolinska HospitalStockholmSweden

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