Zinc-deficiency-induced retinal dysfunction in Crohn's disease
- 22 Downloads
A patient with Crohn's disease and low serum zinc concentrations is presented who had markedly abnormal dark adaptation. Oral zinc supplementation produced an improvement in dark adaptation, and discontinuation of zinc therapy was associated with a worsening of dark adaptation. Serum vitamin A levels were normal throughout this period. We suggest that impaired retinal function is another manifestation of zinc deficiency in Crohn's disease that may be improved with zinc supplementation.
Unable to display preview. Download preview PDF.
- 8.Subcommittee on Medical and Biological Effects of Environment Pollutants, Division of Medical Sciences, Assembly of Life Sciences, National Research Council: Zinc. University Park Press, Baltimore, 1979Google Scholar
- 20.Leure-duPree AE: Electron-opaque inclusions in the rat retinal pigment epithelium after treatment with chelators of zinc. Invest Ophthalmol Vis Sci 21:1–9, 1981Google Scholar
- 21.McClain CJ, Leure-duPree AE, Cameron D: The effect of zinc deficiency on the function and morphology of the eye in rats and man. Clin Res 29:703A, 1981Google Scholar