Digestive Diseases and Sciences

, Volume 24, Issue 11, pp 835–838

The SGOT/SGPT ratio—An indicator of alcoholic liver disease

  • Jerold A. Cohen
  • Marshall M. Kaplan
Original Articles

DOI: 10.1007/BF01324898

Cite this article as:
Cohen, J.A. & Kaplan, M.M. Digest Dis Sci (1979) 24: 835. doi:10.1007/BF01324898


The SGOT/SGPT ratio is significantly elevated in patients with alcoholic hepatitis and cirrhosis (2.85±0.2) compared with patients with postnecrotic cirrhosis (1.74±0.2), chronic hepatitis (1.3±0.17), obstructive jaundice (0.81±0.06) and viral hepatitis (0.74 ±0.07). An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70% of these patients compared with 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis and none with obstructive jaundice.

Copyright information

© Digestive Disease Systems, Inc. 1979

Authors and Affiliations

  • Jerold A. Cohen
    • 1
  • Marshall M. Kaplan
    • 1
  1. 1.Gastroenterology Service, Department of MedicineNew England Medical Center HospitalBoston
  2. 2.Gastroenterology ServiceNew England Medical Center HospitalBoston

Personalised recommendations