Archives of Virology

, Volume 98, Issue 1–2, pp 65–71 | Cite as

Isolation and characterization of caliciviruses from dogs with vesicular genital disease

  • R. A. Crandell
Original Papers


Two virus isolates, one from lesions of the vagina of a Bearded Collie and the other from the penis and prepuce of a Black Labrador, were partially characterized. The two viruses possessed the physicochemical properties, size and morphology of viruses belonging to the family Caliciviridae. The two isolates were shown by cross neutralization tests to be distinct from previously reported canine and feline caliciviruses. The viruses, isolated four years apart, are antigenically related. Additional studies are necessary to determine whether they are two distinct viruses or strains of another serotype belonging to the caliciviruses of the canine species.


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  1. 1.
    Carmichael LE, Strandberg JD, Barnes FD (1965) Identification of a cytopathogenic agent infectious for puppies as a canine herpesvirus. Soc Exp Biol Med 120: 644–650Google Scholar
  2. 2.
    Crandell RA (1967) A description of eight feline picornaviruses and an attempt to classify them. Soc Exp Biol Med 126: 240–245Google Scholar
  3. 3.
    Crandell RA, Madin SH (1960) Experimental studies on a new feline virus. Am J Vet Res 21: 551–556Google Scholar
  4. 4.
    Dawes CJ (1971) Biological techniques in electron microscopy. Harper and Row, New York, NY, pp 1–193Google Scholar
  5. 5.
    Evermann JF, Bryan CM, McKeirnan AJ (1981) Isolation of a calicivrius from a case of canine glossitis. Canine Pract 8: 36–39Google Scholar
  6. 6.
    Eugster AK, Sneed L (1980) Viral intestinal infections of animals and man. Comp Immun Microbiol Infect Dis 2: 417–431Google Scholar
  7. 7.
    Hashimoto A, Hirai K, Fukushi H, Fujimoto Y (1983) The vaginal lesions of a bitch with a history of canine herpesvirus infection. Jpn J Vet Sci 45: 123–126Google Scholar
  8. 8.
    Madin SH, Traum J (1955) Vesicular exanthema of swine. Bact Rev 19: 6–19Google Scholar
  9. 9.
    Poste G, King N (1971) Isolation of a herpesvirus from the canine genital tract: association with infertility, abortion and stillbirths. Vet Rec 88: 229–233Google Scholar
  10. 10.
    Sabin M, Hyne RHJ (1970) Isolation of a feline picornavirus from cheetahs with conjunctivitis and glossitis. Vet Rec 87: 794–796Google Scholar
  11. 11.
    Schaffer FL, Bachrach HL, Brown F, Gillespie JH, Burroughs JN, Madin SH, Madely CR, Povey RC, Scott F, Smith AW, Studdert MJ (1980) Caliciviridae. Intervirology 14: 1–6Google Scholar
  12. 12.
    Schaffer FL, Soergel ME, Black JW, Skilling DE, Smith AW, Cubitt WD (1985) Characterization of a new calicivirus isolated from feces of a dog. Arch Virol 84: 181–195Google Scholar
  13. 13.
    Smith AW, Akers TG, Madin SH, Vedros NA (1973) San Miguel sea lion virus isolation, preliminary characterization and relationship to vesicular exanthema of swine virus. Nature 244: 108–110Google Scholar
  14. 14.
    Smith AW, Prato CM, Skilling DE (1977) Characterization of two new serotypes of San Miguel sea lion virus. Intervirology 8: 30–36Google Scholar
  15. 15.
    Stewart SE, David-Ferrira J, Lovelace E, Landon J, Stock N (1965) Herpes-like virus isolated from neonatal and fetal dogs. Science 148: 1341–1343Google Scholar
  16. 16.
    Traum J (1936) Vesicular exanthema of swine. J Am Vet Med Assoc 41: 316–334Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • R. A. Crandell
    • 1
  1. 1.Texas Veterinary Medical Diagnostic LaboratoryCollege StationUSA

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