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Digestive Diseases and Sciences

, Volume 29, Issue 9, pp 817–823 | Cite as

Kaposi's sarcoma

Gastrointestinal involvement correlation with skin findings and immunologic function
  • R. K. Saltz
  • R. C. Kurtz
  • C. J. Lightdale
  • P. Myskowski
  • S. Cunningham-Rundles
  • C. Urmacher
  • B. Safai
Original Articles

Abstract

We have evaluated 19 homosexual/bisexual male patients with biopsy-proven Kaposi's sarcoma (KS) of the skin in order to define the extent of gastrointestinal involvement and determine its correlation with oral mucosal disease, skin findings, and immunologic function. Nearly half the patients had oral mucosal lesions. In patients with oral mucosal lesions, 75% had gastrointestinal lesions. Some gastrointestinal involvement during the period of observation was present in 10 of the 19 patients. Involvement of the upper gastrointestinal tract was more common than colonic involvement: esophagus 1, stomach 8, duodenum 3, and colon 6. Significant immunosuppression was observed in these patients, measuredin vitro by natural killer (NK) assay, and lymphocyte proliferation response to mitogens.

Keywords

Public Health Sarcoma Natural Killer Gastrointestinal Tract Male Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • R. K. Saltz
    • 1
    • 2
    • 3
    • 4
    • 5
  • R. C. Kurtz
    • 1
    • 2
    • 3
    • 4
    • 5
  • C. J. Lightdale
    • 1
    • 2
    • 3
    • 4
    • 5
  • P. Myskowski
    • 1
    • 2
    • 3
    • 4
    • 5
  • S. Cunningham-Rundles
    • 1
    • 2
    • 3
    • 4
    • 5
  • C. Urmacher
    • 1
    • 2
    • 3
    • 4
    • 5
  • B. Safai
    • 1
    • 2
    • 3
    • 4
    • 5
  1. 1.Gastroenterology Service, Department of MedicineMemorial Sloan-Kettering Cancer CenterNew York
  2. 2.Dermatology Service, Department of MedicineMemorial Sloan-Kettering Cancer CenterNew York
  3. 3.Department of Clinical Immunology and Human ImmunogeneticsMemorial Sloan-Kettering Cancer CenterNew York
  4. 4.Department of PathologyMemorial Sloan-Kettering Cancer CenterNew York
  5. 5.Department of MedicineCornell University Medical CollegeNew York

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