Archives of Virology

, Volume 59, Issue 3, pp 269–274 | Cite as

Antiviral activity of virus-like particles fromLentinus edodes (Shiitake)

  • M. Takehara
  • K. Kuida
  • K. Mori
Brief Report


Interferon (IF) induction and antiviral activity by purified spherical (S) or filamentous (F) virus-like particles and S-derived RNA was studied. A single administration of S particles prior to virus challenge reduced significantly the mortality of mice infected with western equine encephalitis (WEE) virus.


Infectious Disease Interferon Encephalitis Antiviral Activity Single Administration 
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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • M. Takehara
    • 1
  • K. Kuida
    • 2
  • K. Mori
    • 2
  1. 1.Department of MicrobiologyKobe University School of MedicineKobeJapan
  2. 2.Mushroom Research Institute in JapanKiryuJapan

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