Archives of Virology

, Volume 56, Issue 1–2, pp 7–14

Identification and study of a poxvirus isolated from wild rodents in Turkmenia

  • S. S. Marennikova
  • I. D. Ladnyj
  • Z. I. Ogorodnikova
  • E. M. Shelukhina
  • N. N. Maltseva
Original Papers

Summary

A new poxvirus was isolated in 1974 from the kidney of a wild big gerbil(Rhombomys opimus) caught in Turkmenia, where these gerbils are wide-spread. The virus resembles cowpox virus and is markedly different from the virus of infectious ectromelia, the best-known poxvirus of rodents. The new virus is apparently identical to other poxvirus isolates made from white rats andFelidae in the Moscow Zoo.

Experimental inoculation of the natural hosts—big gerbils and yellow susliks(Citellus fulvus)—produced a severe infection with a high mortality rate. Transmission of virus to uninoculated cage mates was shown to occur. Virus persisted in convalescent animals and was present in urine 3 weeks after inoculation and in kidney and testis for at least 5 weeks after inoculation.

The role of rodents as natural hosts of poxviruses is discussed.

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References

  1. 1.
    Baxby, D.: Laboratory characteristics of British and Dutch strains of cowpox virus. Zbl. Vet. Med.B 22, 480–487 (1975).Google Scholar
  2. 2.
    Bedson, H. S., Dumbell, K. R., Thomas, W. R. S.: Variola in Tanganyika. Lancet23 m, 1085–1088 (1963).Google Scholar
  3. 3.
    Kato, S., Takahashi, M., Kameyama, S., Kamahora, I.: A study of the immunological relationships between the inclusions of variola, cowpox, rabbitpox, vaccinia (variola origin) and vaccinia IHD3 and consideration of the term “Guarnieri body”. Biken J.2, 353–363 (1959).Google Scholar
  4. 4.
    Krikun, V. A.: Isolation of pneumotropic virus from rats during the outbreak of disease of unknown etiology in rats nursery. In: Laboratory animals in medical studies. October, Moscow (1974).Google Scholar
  5. 5.
    Ladnyi, I. D., Ogorodnikova, Z. I., Shelukhina, E. M., Gerasimenko, R. T., Voronin, Y. S.: Poxvirus circulation among wild rodents in Turkmenia. Probl. Quarant. Infect.3–4 (43–44, 165–167 (1975).Google Scholar
  6. 6.
    Marennikova, S. S., Shenkman, L. S., Shelukhina, E. M., Maltseva, N. N.: Isolation of camelpox virus and investigation of its properties. Acta virol.18, 423–428 (1974).Google Scholar
  7. 7.
    Marennikova, S. S., Maltseva, N. N., Korneeva, V. I., Garanina, N. M.: Pox infection in carnivora of the family Felidae. Acta virol.19, 260 (1975).Google Scholar
  8. 8.
    Marennikova, S. S., Shelukhina, E. M.: White rats—a source of pox infection in carnivora of Felidae family. Acta virol.20, 442 (1976).Google Scholar
  9. 9.
    Marennikova, S. S., Shelukhina, E. M., Shenkman, L. S.: “White wild” (variola-like) pox viruses in rodents of Equatorial Africa. Acta virol.20, 80–82 (1976).Google Scholar
  10. 10.
    Marennikova, S. S., Shelukhina, E. M.: Susceptibility of some rodent species to monkeypox virus and the course of infection. Bull. WHO53, 13–19 (1976).Google Scholar
  11. 11.
    Marennikova, S. S., Shelukhina, E. M.: Pox infection in white rats. Brit. vet. J. (in press).Google Scholar
  12. 12.
    Shafikova, R. D., Marennikova, S. S.: Characteristics of properties of variola virus isolated from patients with different forms of disease. Vopr. Virusol.6, 699 to 702 (1970).Google Scholar

Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • S. S. Marennikova
    • 1
  • I. D. Ladnyj
    • 1
  • Z. I. Ogorodnikova
    • 1
  • E. M. Shelukhina
    • 1
  • N. N. Maltseva
    • 1
  1. 1.WHO Collaborating Center on Smallpox and Other Poxvirus InfectionsMoscow Research Institute of Virus Preparations, Ministry of Public HealthMoscowUSSR

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