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Digestive Diseases and Sciences

, Volume 28, Issue 2, pp 174–182 | Cite as

Pill-induced esophageal injury

Case reports and review of the medical literature
  • James Walter Kikendall
  • Arnold C. Friedman
  • Morakinyo Anthony Oyewole
  • David Fleischer
  • Lawrence F. Johnson
Original Articles

Abstract

We report four cases of esophageal injury associated with the ingestion of commonly prescribed tablets or capsules. History and clinical characteristics of these cases suggest that the medications failed to transit the esophagus and acted locally to produce esophagitis. A search of English- and foreign-language medical journals documented 221 similar cases due to 26 different types of medication. While most of these esophageal injuries are self-limited and produce no morbidity beyond transient retrosternal pain, odynophagia, and dysphagia, major complications have occurred, such as mediastinal penetration, hemorrhage, and death. Patients should be counseled to take pills in an upright posture with liberal amounts of fluid well before retiring for the night.

Keywords

Public Health Medical Journal Major Complication Esophagitis Similar Case 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Digestive Disease Systems, Inc. 1983

Authors and Affiliations

  • James Walter Kikendall
    • 1
    • 2
    • 3
  • Arnold C. Friedman
    • 1
    • 2
    • 3
  • Morakinyo Anthony Oyewole
    • 1
    • 2
    • 3
  • David Fleischer
    • 1
    • 2
    • 3
  • Lawrence F. Johnson
    • 1
    • 2
    • 3
  1. 1.Gastroenterology and Radiology DivisionsWalter Reed Army Medical CenterWashington, D.C.
  2. 2.the Uniformed Services University of the Health SciencesWashington, D.C.
  3. 3.the Gastroenterology/Hepatology SectionVeterans Administration Medical CenterWashington, D.C.

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