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Archives of Virology

, Volume 68, Issue 3–4, pp 239–247 | Cite as

Principles of selective inactivation of viral genome

I. UV-induced inactivation of influenza virus
  • E. I. Budowsky
  • S. E. Bresler
  • E. A. Friedman
  • N. V. Zheleznova
Original Papers

Summary

Photosensitivity of infectious, haemagglutinating and neuraminidase activities of influenza virus has been determined experimentally. The photosensitivity of infectious activity of type B (strain Hongkong/8/73) influenza virus was found to be higher than that of type A strains NIB-4 (H3N2–3), Leningrad/399/76 (H3N2–3) and NIB-6 (H1N1). The data obtained may be used for the determination of conditions of UV-irradiation for preparation of UV-inactivated antiviral vaccines.

Keywords

Infectious Disease Influenza Influenza Virus Viral Genome Neuraminidase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • E. I. Budowsky
    • 1
  • S. E. Bresler
    • 2
  • E. A. Friedman
    • 3
  • N. V. Zheleznova
    • 3
  1. 1.M. M. Shemyakin Institute of Bioorganic ChemistryAcademy of Sciences of the U.S.S.R.MoscowUSSR
  2. 2.Institute of Nuclear PhysicsAcademy of Sciences of the U.S.S.R.LeningradUSSR
  3. 3.Pasteur Institute of Epidemiology and MicrobiologyLeningradUSSR

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