Advertisement

Archives of Virology

, Volume 68, Issue 3–4, pp 189–195 | Cite as

Isolation of an influenza A virus from seals

  • G. Lang
  • A. Gagnon
  • J. R. Geraci
Original Papers

Summary

Influenza A virus of serotype Hav1 Neq1 (H7N7 by the 1980 revised influenza typing system proposed by WHO experts) was repeatedly isolated from lung and brain tissues taken from harbor seals (Phoca vitulina) found suffering from pneumonia on Cape Cod Peninsula (U.S.A.) in the winter of 1979–1980. The seal isolates, although of a serotype identical to some fowl plague virus strains, were harmless to chickens and turkeys in transmission experiments. An earlier human infection by a Hav1 Neq1 influenza virus and the serologic relatedness of this avian serotype with the equine 1 serotype are cited in support of the view that influenza viruses with these antigenic characteristics seem to have a facility to pass from birds to mammals.

Keywords

Infectious Disease Pneumonia Influenza Brain Tissue Influenza Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bahl, A. K., Pomeroy, B. S., Mangundimedjo, S., Easterday, B. C.: Isolation of type A influenza and Newcastle disease viruses from migratory waterfowl in the Mississippi flyway. J. Amer. vet. med. Ass.177, 949–951 (1977).Google Scholar
  2. 2.
    Boudreault, A., Lecomte, J., Hinshaw, V. S.: Caractérisation antigénique des virus influenza A isolés des oiseaux capturés dans l'Ontario, le Québec et les Provinces Maritimes durant la saison 1977. Rev. Can. Biol.39, 107–114 (1980).Google Scholar
  3. 3.
    Butterfield, W. K., Campbell, C. H.: Relationship of influenza A viruses of avian subtype 1 hemagglutinin including fowl plague viruses. Vet. Microbiol.4, 101–107 (1979).Google Scholar
  4. 4.
    Campbell, C. H., Webster, R. G., Breese, S. S.: Fowl plague virus from man. J. inf. Dis.122, 513–516 (1970).Google Scholar
  5. 5.
    DeLay, P. D., Casey, H. L., Tubiash, H. S.: Comparative study of fowl plague virus and a virus isolated from man. Pbl. Hlth. Rep.82, 615–620 (1967).Google Scholar
  6. 6.
    Dinter, Z.: Über die Beziehungen des Virus N zu dem Virus der klassischen Geflügelpest. Berlin. Münch. Tierärztl. Wschr. 1950, 101–113 (1950).Google Scholar
  7. 7.
    Easterday, B. C.: Animal Influenza. In:Kilbourne, E. D. (ed.), The Influenza Viruses and Influenza, 449–481. New York: Academic Press 1975.Google Scholar
  8. 8.
    Geraci, J. R., St. Aubin, D. J., Webster, R. G., Madoff, S., Barker, I. K., Prescott, J. R.: A mass mortality of seals associated with influenza virus and mycoplasma. (Submitted to Science.)Google Scholar
  9. 9.
    Gimenez, D. F.: Staining rickettsiae in yolk sac cultures. Stain Technol.39, 135 to 140 (1964).Google Scholar
  10. 10.
    Lvov, D. K., Zdanov, V. M., Sazonov, A. A. et al. Comparison of influenza viruses isolated from man and from whales. Bull. Wld. Hlth. Org.56, 923–930 (1978).Google Scholar
  11. 11.
    Narayan, O., Lang, G., Rouse, B.: A new influenza A virus infection in turkeys. V. Pathology of the experimental disease by strain turkey, Ontario 7732/66. Arch. ges. Virusforsch.26, 166–182 (1969).Google Scholar
  12. 12.
    Narayan, O.: Pathogenesis of lethal influenza virus infection in turkeys. II. Central nervous system phase of infection. J. Comp. Pathol.82, 139–146.Google Scholar
  13. 13.
    Palmer, D. F., Coleman, M. T., Dowdle, W. R., Schild, G. G.: Advanced Laboratory Techniques for Influenza Diagnosis. U.S. Dept. of Health, Education and Welfare (Immunology Series No. 6) (1975).Google Scholar
  14. 14.
    Rott, R., Becht, H., Orlich, M.: Antigenic relationship between the surface antigens of avian and equine influenza viruses. Med. Microbiol. Immunol.161, 253–261 (1975).Google Scholar
  15. 15.
    Sazanov, A. A., Lvov, D. K., Broude, N. A., Portyanko, N. V., Yamicova, S. S., Timofeeva, A. A., Sokolava, T. V., Pogrebenko, A. G.: Data on virological and serological examination of seabirds and fur seals in Tyuleryi Island of Sakhalinsk region. In:Lvov, D. K. (ed.), Ecology of Viruses. The D. I. Ivanovsky Institute of Virology, Vol. 4, 157–160 (1976).Google Scholar
  16. 16.
    Schild, G. C., Newman, R. W., Webster, R. G., Major, D., Hinshaw, V. S.: Antigenic analysis of influenza A virus surface antigens. Considerations for the nomenclature of influenza virus. Arch. Virol.63, 171–184 (1980).Google Scholar
  17. 17.
    Scholtissek, C.: The genome of influenza virus. Curr. Top. Microbiol. Immunol.80, 139–169 (1978).Google Scholar
  18. 18.
    Slemons, R. D., Easterday, B. C.: Type A influenza viruses in the feces of migratory waterfowl. J. Amer. vet. med. Ass.171, 947–948 (1977).Google Scholar
  19. 19.
    Thorsen, J., Barker, I. K., Hinshaw, V. S.: Influenza viruses isolated from waterfowl in southern Ontario 1976–78. Can. J. Microbiol.26, 1511–1514 (1980).Google Scholar
  20. 20.
    Webster, R. G., Laver, W. G.: Antigenic variations of influenza viruses. In:Kilbourne, E. D. (ed.), The Influenza Viruses and Influenza, 209–314. New York: Academic Press 1975.Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • G. Lang
    • 1
  • A. Gagnon
    • 2
  • J. R. Geraci
    • 3
  1. 1.Department of Veterinary Microbiology and ImmunologyOntario Veterinary College University of GuelphGuelphCanada
  2. 2.Ontario Ministry of Agriculture and FoodVirus Laboratory, Veterinary Services BranchOntarioCanada
  3. 3.Department of Pathology, Ontario Veterinary CollegeUniversity of GuelphOntarioCanada

Personalised recommendations