Digestive Diseases and Sciences

, Volume 31, Issue 4, pp 343–348

Gastric emptying and gastrointestinal absorption of alcohol ingested with a meal

  • Antoine Cortot
  • Gilles Jobin
  • Frederic Ducrot
  • Chantal Aymes
  • Veronique Giraudeaux
  • Robert Modigliani
Original Articles

DOI: 10.1007/BF01311667

Cite this article as:
Cortot, A., Jobin, G., Ducrot, F. et al. Digest Dis Sci (1986) 31: 343. doi:10.1007/BF01311667

Abstract

We have measured, by an intubation method, gastric evacuation and gastrointestinal absorption of alcohol ingested with a meal in seven healthy nonalcoholic subjects. A homogenized meal containing [14C]PEG and ethanol (1 g/kg body wt) was given intragastrically while saline containing [57CO]vitamin B12 was perfused into the duodenum. Of the ingested alcohol, 39.4±4.1% was absorbed through the stomach wall during the first postprandial hour and 73.2±4.2% during the total postcibal period, whereas only 24±3% was absorbed during the same time in the duodenum. Thus alcohol ingested with a meal is mainly and rapidly absorbed in the stomach; the contribution of the small intestine below the angle of Treitz to alcohol absorption is negligible.

Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Antoine Cortot
    • 1
  • Gilles Jobin
    • 1
  • Frederic Ducrot
    • 1
  • Chantal Aymes
    • 1
  • Veronique Giraudeaux
    • 1
  • Robert Modigliani
    • 1
  1. 1.INSERM U 54Hôpital Saint-LazareParis Cedex 10France

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