Archives of Virology

, Volume 109, Issue 1–2, pp 115–120 | Cite as

Morphological characterization of chicken anaemia agent (CAA)

  • H. Gelderblom
  • S. Kling
  • R. Lurz
  • I. Tischer
  • V. v. Bülow
Brief Report


Chicken anaemia agent (CAA) was characterized as a virion with 25nm in diameter, with a buoyant density in CsCl of 1.36–1.37 g/cm3, and containing a circular, single-stranded DNA genome. The virus is composed of 32 hollow morphological units representing a regular T=3 icosahedron.


Infectious Disease CsCl Morphological Characterization Buoyant Density Morphological Unit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Bülow Vv, Fuchs B, Vielitz E, Landgraf H (1983) Frühsterblichkeitssyndrom bei Küken nach Infektion mit dem Virus der Marekschen Krankheit (MDV) und einem Anämie-Erreger (CAA). Zentralbl Vet Med B 30: 742–750Google Scholar
  2. 2.
    Bülow Vv, Fuchs B, Bertram M (1985) Untersuchungen über den Erreger der infektiösen Anämie bei Hühnerküken (CAA) in vitro: Vermehrung, Titration, Serumneutralisationstest und indirekter Immunfluoreszenztest. Zentralbl Vet Med B 32: 679–693Google Scholar
  3. 3.
    Bülow Vv, Fuchs B, Rudolph R (1986) Avian infectious anaemia caused by chicken anaemia agent (CAA). In: McFerran JB, McNulty MS (eds) Acute virus infections of poultry. Martinus Nijhoff, Dordrecht, pp 203–212Google Scholar
  4. 4.
    Carter MJ, Madeley CR (1987) Caliciviridae. In: Nermut MV, Steven AC (eds) Animal virus structure. Elsevier, Amsterdam (Perspectives in medical virology, vol 3, pp 121–128)Google Scholar
  5. 5.
    Cubitt WD, Barrett ADT (1985) Propagation and preliminary characterization of a chicken candidate calicivirus. J Gen Virol 66: 1431–1438Google Scholar
  6. 6.
    Gelderblom H, Bauer H, Frank H, Wigand R (1967) The structure of group II adenoviruses. J Gen Virol 1: 553–560Google Scholar
  7. 7.
    Goryo M, Sugimura H, Matsumoto S, Umemura T, Itakura C (1985) Isolation of an agent inducing chicken anaemia. Avian Pathol 14: 483–496Google Scholar
  8. 8.
    Goryo M, Suwa T, Matsumoto S, Umemura T, Itakura C (1987) Serial propagation and purification of chicken anaemia agent in MDCC-MSB1 cell line. Avian Pathol 16: 149–163Google Scholar
  9. 9.
    Maniatis T, Fritsch EF, Sambrock J (1982) Molecular cloning. A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New YorkGoogle Scholar
  10. 10.
    McNulty MS, Connor TJ, McNeilly F, Todd D, Mawhinney KA, Creelan J, Mackie DP, Pollock D, McNair J, Curran WL, McLoughlin MF (1989) Current status of chicken anemia agent. In: Proceedings of the 38th Western Poultry Disease Conference, Tempe, Arizona, March 6–9, 1989, pp 12–13Google Scholar
  11. 11.
    Ritchie BW, Niagro FD, Lukert PD, Steffens III WL, Latimer KS (1989) Characterization of a new virus from cockatoos with psittacine beak and feather disease. Virology 171: 83–88Google Scholar
  12. 12.
    Schaffer FL, Bachrach HL, Brown F, Gillespie JH, Burroughs JN, Madin SH, Madeley CR, Povey RC, Scott F, Smith AW, Studdert MJ (1980) Caliciviridae. Intervirology 14: 1–6Google Scholar
  13. 13.
    Spiess E, Lurz R (1988) Electron microscopic analysis of nucleic acids and nucleic acidprotein complexes. In: Mayer F (ed) Electron microscopy in microbiology. Academic Press, London (Methods in microbiology, vol 20, pp 293–323)Google Scholar
  14. 14.
    Tischer I, Gelderblom H, Vettermann W, Koch MA (1982) A very small porcine virus with circular single-stranded DNA. Nature 295: 64–66Google Scholar
  15. 15.
    Yuasa N, Taniguchi T, Yoshida I (1979) Isolation and some characteristics of an agent inducing anemia in chicks. Avian Dis 23: 366–385Google Scholar

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • H. Gelderblom
    • 1
  • S. Kling
    • 2
  • R. Lurz
    • 3
  • I. Tischer
    • 1
  • V. v. Bülow
    • 2
  1. 1.Robert-Koch-Institut des BundesgesundheitsamtesBerlin
  2. 2.Institut für GeflügelkrankheitenFreie Universität BerlinBerlin
  3. 3.Max-Planck-Institut für Molekulare GenetikBerlin

Personalised recommendations