Archives of Virology

, Volume 125, Issue 1–4, pp 331–338 | Cite as

Genomic rearrangements in human rotavirus strain Wa; analysis of rearranged RNA segment 7

  • E. Méndez
  • C. F. Arias
  • S. López
Brief Report


Two rotavirus variants containing genomic rearrangements were isolated from human rotavirus strain Wa. In one variant (H5) the rearrangement involves the RNA segment 5, while in the other variant (H57) two genes, 5 and 7 are rearranged. The rearranged genes are composed exclusively of sequences from the genes they substitute. Sequence analysis of the rearranged segment 7 indicated that it is a partial duplication of the wild type gene, in a head-to-tail orientation.


Infectious Disease Sequence Analysis Type Gene Rearrange Gene Genomic Rearrangement 
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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • E. Méndez
    • 1
  • C. F. Arias
    • 1
  • S. López
    • 1
  1. 1.Departamento de Biología Molecular, Centro de Investigación sobre Ingeniería Genética y BiotecnologíaUniversidad Nacional Autónoma de MéxicoCuernavaca, MorelosMexico

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