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Digestive Diseases and Sciences

, Volume 38, Issue 1, pp 45–50 | Cite as

Relation of symptoms to impaired stomach, small bowel, and colon motility in long-standing diabetes

  • Frank L. Iber
  • Shahla Parveen
  • Mark Vandrunen
  • K. B. Sood
  • Farooq Reza
  • Rose Serlovsky
  • Sudhir Reddy
Original Articles

Abstract

Stomach, intestinal, and colonic transit were measured in males with insulin-requiring diabetes of greater than 10 years' duration to compare with symptoms and to estimate the medical significance. For all diabetics only the symptom constipation correlated with the appropriate regional delayed transit. Diabetics with delayed transit in any region, however, had more overall gastrointestinal symptoms. Diabetics with delayed transit had disease of significantly longer duration than those without delay. Delayed transit was common in the diabetics selected for study with 21 of 54 stomachs, 10 of 20 small intestines, and 14 of 20 colons showing impairment. Of 35 diabetics with impaired transit at one or more locations, only seven were judged of medical importance and five of these responded to treatment. In this study, delayed transit was frequent; in the one fifth requiring management, the symptoms related closely to the region impaired.

Key Words

delayed gastric emptying delayed small intestinal transit delayed colon transit early satiety indigestion constipation insulin-requiring diabetics autonomic neuropathy long-standing diabetes 

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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • Frank L. Iber
    • 1
  • Shahla Parveen
    • 1
  • Mark Vandrunen
    • 1
  • K. B. Sood
    • 1
  • Farooq Reza
    • 1
  • Rose Serlovsky
    • 1
  • Sudhir Reddy
    • 1
  1. 1.Division of Gastroenterology and Departments of Medicine, Nuclear Medicine and Radiology Edward HinesVA HospitalHines

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