Abstract
A prospective, one-month diary study was conducted with 23 adult irritable bowel syndrome (IBS) patients in order to determine the relationship between IBS and the quality of sleep. Subjects were screened through history and diagnostic studies. Accepted patients then completed a daily diary of IBS symptoms and sleep quality. At baseline, most subjects (74%) characterized themselves as “poor sleepers”. Using pooled time series analysis, the study found a significant correlation between morning IBS symptoms and the quality of the prior night's sleep (P<0.001), a finding not previously reported in the literature. A less strong but still significant correlation (P<0.05) was found between end of day IBS symptoms and the quality of sleep during the prior evening. Morning IBS symptoms seem to rise or fall in close association with the prior night's quality of sleep. The study supports the hypothesis that IBS symptoms are related to a disturbance in sleep.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Drossman DA, Sandler RS, McKee DC, Lovitz AJ: Bowel dysfunction amongst subjects not seeking health care. Gastroenterology 83:529–534, 1982
Hislop IG: Psychological significance of the irritable bowel syndrome. Gut 12:452–457, 1971
Young J, Alpers DH, Norland MS, Woodruff RA: Psychiatric illness and the irritable bowel syndrome: Practical implications for the primary care physician. Gastroenterology 80:1068–1069, 1981
Drossman DA, Sandler RS: Irritable bowel syndrome: The role of psychosocial factors.In Irritable Bowel Syndrome. NW Read (ed). London, Grune & Stratton, 1985
Harvey RF, Read AE: Effect of cholecystokinin on colonic motility and symptoms in patients with irritable bowel syndrome. Lancet 1:1–3, 1977
Sullivan MA, Cohen A, Snape WJ: Colonic myoelectrical activity in the irritable bowel syndrome; effect of eating and anti-cholingerics. N Engl J Med 298:878–883, 1978
Whitehead WE, Cheskin LJ, Heller BR, Robinson JC, Crowell MD, Benjamin C, Schuster MM: Evidence for exacerbation of irritable bowel syndrome during menses. Gastroenterology 98:1485–1489, 1990
Goo RH, Moore JG, Greenberg E, Alazraki NP: Circadian variation in gastric emptying of meals in humans. Gastroenterology 93:515–518, 1987
Narducci F, Bassotti G, Caburri M, Morell A: Circadian rhythms of the human colonic motility. 10th international symposium on gastrointestinal motility. Dig Dis Sci 30(8):784, 1985 (abstract)
Kumar D, Wingate DL, Ruckebusch Y: Circadian variation in the propagation velocity of the migrating motor complex. Gastroenterology 91:926–930, 1986
Roberts-Thompson IC, Kennaway DJ, Knight RE, Pannall PR: Circadian rhythms in patients with abdominal pain syndrome. Aust NZ J Med 18:569–574, 1988
Manning AP, Thompson WG, Heaton KW, Morris AF: Towards positive diagnosis of the irritable bowel. Br Med J 6138:653–654, 1978
Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J: An inventory for measuring depression. Arch Gen Psychiatry (Chicago) 4:561–571, June 1961
Spielberger CD: State-trait anxiety inventory form Y, assessment, counseling and training materials. Consulting Psychologists Press Inc., Palo Alto, CA, 1988
SAS Institute. VMS SAS Production Release 5–18 (software). Cary, NC, SAS Institute, 1988
Frederiksen CH, Rotundo JA: Time-Series models and the study of longitudinal change.In Longitudinal Research in the Study of Behavior and Development. JR Nesselroode, BP Baltes (eds). New York, Academic Press, 1979, pp 111–153
Ostrom CW Jr: Time Series Analysis: Regression Techniques, 2nd ed. Newbury Park, California, Sage Publications, 1990
Sayrs LW: Pooled Time Series Analysis. Newbury Park, California, Sage Publications, 1989
Kessler RC, Greenbert DF: Linear Panel Analysis: Models of Quantitative Change. New York, Academic Press, 1981, pp 157–163
Hannan MT, Young AA: Estimation in panel models: Results on pooling cross-sections and time series.In DR Heise (ed). Sociological Methodology 1977. San Francisco, Jossey-Bass Publishers, 1977, pp 52–83
Drummond DJ, Gallant AR: The TSCREG procedure.In SUGI Supplemental Library User's Guide, Version 5 Edition. Cary, North Carolina, SAS Institute, 1986, pp 625–645
Roche Labs: Psychiatric Rating Scales. Nutley, New Jersey, Roche, Inc., 1984
Williamson HA, Williamson MT: The Beck Depression Inventory: Normative data and problems with generalizability. Fam Med 21(1):58–60, 1989
Nielsen AC, Williams TA: Depression in ambulatory medical patients: prevalence by self-report questionnaire and recognition by nonpsychiatric physicians. Arch Gen Psychiatry 37:999–1004, 1980
Spielberger CD: Manual for the State-Trait Anxiety Inventory. Palo Alto, California, Consulting Psychologists Press Inc., 1983
Whitehead WE, Schuster M (eds): Gastrointestinal Disorders. Orlando, Florida, Academic Press, 1985
Chaudhary NA, Truelove SC: Q J Med 31:307–332, 1962
Saletu B: Is the subjectively experienced quality of sleep related to objective sleep parameters? Behav Biol 13:433–444, 1975 (abstract 4222)
Johns MW: Factor analysis of objective and subjective characteristics of a night's sleep. Psychol Med 5:413–418, 1975
Williams RL, Karacan I, Moore CA: Sleep Disorders-Diagnosis and Treatment, 2nd ed. New York, John Wiley & Sons, 1988
Maxton DG, Morris J, Whorwell PJ: More accurate diagnosis of irritable bowel syndrome by use of “non-colonic” symptomatology. Gut 32:784–786, 1991
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Goldsmith, G., Levin, J.S. Effect of sleep quality on symptoms of irritable bowel syndrome. Digest Dis Sci 38, 1809–1814 (1993). https://doi.org/10.1007/BF01296103
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01296103