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Digestive Diseases and Sciences

, Volume 38, Issue 6, pp 1152–1155 | Cite as

Splenic infarction associated with anticardiolipin antibodies in a patient with acquired immunodeficiency syndrome

  • Mitchell S. Cappell
  • Todd Simon
  • Moti Tiku
Case Report

Summary

Although patients with AIDS frequently develop high titers of anticardiolipin antibodies, the clinical significance of this laboratory abnormality in AIDS patients is unknown. A 33-year-old female with AIDS, a prior small cerebrovascular accident, thrombocytopenia, and a coagulopathy suddenly developed left upper quadrant pain and tenderness due to splenic infarction associated with a high titer of anticardiolipin antibodies. Possible clinical manifestations of anticadiolipin antibodies in this patient include recurrent thromboembolism, coagulopathy, and thrombocytopenia. This case report suggests that anticardiolipin antibodies are associated with splenic infarction and that anticardiolipin antibodies associated with AIDS may sometimes be clincally signifcant.

Key Words

anticardiolipin antibodies lupus anticoagulant systemic lupus erythematosus vasculitis autoimmune diseases human immunodeficiency virus acquired immunodeficiency syndrome splenc infarction thromboembolism 

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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • Mitchell S. Cappell
    • 1
  • Todd Simon
    • 1
  • Moti Tiku
    • 1
  1. 1.Divisions of Gastroenterology & Rheumatology, Department of MedicineUMDNJ-Robert Wood Johnson (formerly Rutgers) Medical SchoolNew Brunswick

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