Journal of Neural Transmission

, Volume 104, Issue 2–3, pp 191–197 | Cite as

Transcranial magnetic stimulation induces alterations in brain monoamines

  • D. Ben-Shachar
  • R. H. Belmaker
  • N. Grisaru
  • E. Klein
Short Communication Basic Neurosciences and Genetics


Transcranial magnetic stimulation has been suggested as a possible therapeutic tool in depression. In behavioral models of depression, magnetic stimulation induced similar effects to those of electroconvulsive shock. This study demonstrates the effect of a single session of rapid TMS on tissue monoamines in rat brain. Alterations in monoamines were selective and specific in relation to brain areas and type of monoamine. The results imply on a biochemical basis to the suggested ECT-like treatment potential of TMS.


Transcranial magnetic stimulation (TMS) brain monoamines electroconvulsive shock (ECS) depression rat 


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Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • D. Ben-Shachar
    • 1
  • R. H. Belmaker
    • 2
  • N. Grisaru
    • 2
  • E. Klein
    • 1
  1. 1.Laboratory of Psychobiology, Faculty of Medicine, Technion, Department of PsychiatryRambam Medical CenterIsrael
  2. 2.Ministry of Health, Mental Health Center Beer-Sheva, Faculty of Health SciencesBen-Gurion University of the NegevBeer-ShevaIsrael

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