Effect of quartz and asbestos on erythrocyte surface charge

  • Silvia Gabor
  • T. Frits
  • Zoe Anca


Experiments in vitro have been conducted to determine the surface-charge density of human red cells incubated with 7 quartz varieties as well as the UICC asbestos dusts: chrysotiles A and B, anthophyllite, amosite, and crocidolite. Red cell mobility was measured by capillary migration on Whatman paper strips and by electrophoresis. All dusts tested significantly decreased the erythrocyte surface electric charge as compared to control samples that were free of dust.

Pretreatment of quartz dust with Polyvinylpyridine-N-Oxide restored the electronegativity of erythrocytes. The results obtained provide support for the cytotoxic effect of quartz and asbestos on the external cell membrane.

Key words

Quartz Asbestos Surface Charge Electrophoretic Mobility Erythrocytes 


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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • Silvia Gabor
    • 1
  • T. Frits
    • 1
  • Zoe Anca
    • 1
  1. 1.Institute of Hygiene and Public HealthClujRomania

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