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Journal of Neural Transmission

, Volume 33, Issue 2, pp 163–178 | Cite as

The balance of biogenic amines as condition for normal behaviour

  • W. Birkmayer
  • W. Danielczyk
  • E. Neumayer
  • P. Riederer
Article

Summary

An accumulation of norepinephrin, serotonin and dopamin exists in the brainstem. A decrease of biogenic amines in the brains of Parkinson's cases has been demonstrated. A substitution by the precursor L-DOPA produces an increase of dopamin in the brain and a decrease of serotonin. The high level of dopamin improves the akinesia and the depletion of serotonin causes a toxic delir. A substitution by l-tryptophan restores the balance and the Dopa-psychosis disappears.

Keywords

Public Health Serotonin Biogenic Amine Normal Behaviour Norepinephrin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1972

Authors and Affiliations

  • W. Birkmayer
    • 1
  • W. Danielczyk
    • 1
  • E. Neumayer
    • 1
  • P. Riederer
    • 1
  1. 1.Ludwig-Boltzmann-Institut für Neurochemie und neurologische Abteilung des Alterskrankenhauses der Stadt Wien-LainzÖsterreich

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