Archiv für die gesamte Virusforschung

, Volume 30, Issue 4, pp 327–342

A Respiratory syncytial virus of bovine origin

  • M. F. Paccaud
  • Cl. Jacquier
Article

Summary

An outbreak of respiratory disease which spread to all cattle aged less than 7 years in two farms, in the village of Avusy (canton of Geneva), is briefly described. The course of the disease was more severe in older animals, which showed frequently symptoms of bronchopneumonia, than in younger ones. The disease lasted from 3 to 10 days. No deaths were reported.

A virus antigenically related to the human respiratory syncytial viruses was isolated from the conjunctivo-nasal specimens of one animal in each farm. Evidence of the bovine origin of both strains was brought by the sero-conversions displayed by the cattle under study in neutralization and complement fixation tests and by some biological traits of the virus as well.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bloth, B., Å. Espmark, E. Norrby, andS. Gard: The ultrastructure of respiratory syncytial (RS) virus. Arch. ges. Virusforsch.13, 582–586 (1963).CrossRefPubMedGoogle Scholar
  2. 2.
    Bonissol, C.: Etude de cellules KB infectées par les Myxovirus parainfluenzae de type II et III et le virus respiratoire synoytial. II. Etude cytochimique. Ann. Inst. Pasteur111, 265–281 (1966).Google Scholar
  3. 3.
    Chanock, K., B. Roizman, andR. Myers: Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). I. Isolation, properties and characterization. Amer. J. Hyg.66, 281–290 (1957).PubMedGoogle Scholar
  4. 4.
    Chanock, R. M., W. D. James, H. H. Fox, H. C. Turner, M. A. Mufson, andL. Hayflick: Growth of Eaton PPLO in broth and preparation of complement fixing antigen. Proc. Soc. exp. Biol. (N.Y.)110, 884–889 (1962).CrossRefGoogle Scholar
  5. 5.
    Chanock, R. M., M. A. Mufson, W. D. James, H. H. Fox, H. H. Bloom, andB. Forsyth: Recovery of PPLO to atypical pneumonia on artificial agar medium. Proc. Soc. exp. Biol. (N.Y.)110, 543–547 (1962).CrossRefGoogle Scholar
  6. 6.
    Chanock, R. M., M. A. Mufson, andK. M. Johnson: Comparative biology and ecology of human virus and mycoplasma respiratory pathogens. Progr. med. Virol.7, 208–252 (1965).Google Scholar
  7. 7.
    Desprès, P., M. F. Paccaud etB. Poncioni: Zoonoses brucellique, rickettsienne et bedsonienne et leurs rapports avec quelques parasitoses fréquemment rencontrées chez le mouton suisse. Schweiz. Arch. Tierheilk.104, 569–584 (1962).Google Scholar
  8. 8.
    Doggett, J. E., D. Taylor-Robinson, andR. G. C. Gallop: A study of an inhibitor in bovine serum active against respiratory synoytial virus. Arch. ges. Virusforsch.23, 126–137 (1968).CrossRefPubMedGoogle Scholar
  9. 9.
    Dougherty, E. M.: Preservation of cells in tissue culture. Use of dimethyl sulfoxyde for preservation of tissue culture cells by freezing. Nature (Lond.)193, 550–552 (1962).CrossRefGoogle Scholar
  10. 10.
    Dulbecco, R., andM. Vogt: Plaque formation and isolation of pure lines with poliomyelitis viruses. J. exp. Med.99, 167–182 (1954).CrossRefPubMedPubMedCentralGoogle Scholar
  11. 11.
    Eagle, H.: Amino acid metabolism in mammalian cell cultures. Science130, 432–437 (1959).CrossRefPubMedGoogle Scholar
  12. 12.
    Gharpure, M. A., P. F. Wright, andR. M. Chanock: Temperature-sensitive mutants of respiratory syncytial virus. J. Virol.3, 414–421 (1969).PubMedPubMedCentralGoogle Scholar
  13. 13.
    Grist, N. R., C. A. C. Ross, E. J. Bell, andE. J. Stott: In: Diagnostic Methods in Clinical Virology (Blackwell, Oxford, 1966).Google Scholar
  14. 14.
    Gundelfinger, B. F., M. J. Hantover, J. A. Bell, C. G. Loosli, andW. P. Rowe: Evaluation of a trivalent adenovirus vaccine for prevention of acute respiratory disease in naval recruits. Amer. J. Hyg.68, 156–168 (1958).PubMedGoogle Scholar
  15. 15.
    Hallauer, C., andG. Kronauer: Extraction of cell-associated virus without damage of the culture. Arch. ges. Virusforsch.15, 433–440 (1965).CrossRefPubMedGoogle Scholar
  16. 16.
    Hayflick, L., andP. S. Moorhead: The serial cultivation of human diploid cell strains. Exp. Cell Res.25, 585–621 (1961).CrossRefPubMedGoogle Scholar
  17. 17.
    Hornsleth, A.: Acceleration of the growth of respiratory syncytial virus by proflavine. J. Path. Bact.92, 210–217 (1966).CrossRefPubMedGoogle Scholar
  18. 18.
    Jordan, W. S., Jr.: Growth characteristics of respiratory syncytial virus. J. Immunol.88, 581–590 (1962).PubMedGoogle Scholar
  19. 19.
    Kapikian, A. Z., R. H. Mitchell, R. M. Chanock, R. A. Shevedoff, andC. E. Stewart: An epidemiological study of altered clinical reactivity to respiratory syncytial (ES) virus infection in children previously vaccinated with an inactivated RS virus vaccine. Amer. J. Epidem.89, 405–421 (1969).Google Scholar
  20. 20.
    Kerr, K. M., C. C. Mascoli, N. O. Olson, andA. Campbell: Rapid specific agglutination of Eaton agent (Mycoplasma pneumoniae). J. Bact.87, 478–479 (1964).PubMedPubMedCentralGoogle Scholar
  21. 21.
    Kisch, A. L., K. M. Johnson, andR. M. Chanock: Immunofluorescence with respiratory syncytial virus. Virology16, 177–189 (1962).CrossRefPubMedGoogle Scholar
  22. 22.
    Morris, J. A., R. E. Blount, Jr., andR. E. Savage: Recovery of cytopathogenic agent from chimpanzees with coryza. Proc. Soc. exp. Biol. (N.Y.)92, 544–549 (1956).CrossRefGoogle Scholar
  23. 23.
    Paccaud, M. F.: Observations sur la culture de cellules humaines en lignée continue et sur leur sensibilité à certains virus. Progr. immunobiol. Standard.1, 140–146 (Karger, Basel/New York 1964).Google Scholar
  24. 24.
    Penso, G., eD. Balducci: In: Le Colture dei Tessuti nella Ricerca Biologica. (II Pensiero Scientifico, Roma 1962).Google Scholar
  25. 25.
    Pollard, M., andTh. J. Starr: Study of intracellular virus with acridine orange fluorochrome. Progr. med. Virol.4, 54–69 (1962).Google Scholar
  26. 26.
    Reed, L. J., andH. Muench: A simple method of estimating fifty per cent endpoints. Amer. J. Hyg.27, 493–497 (1938).Google Scholar
  27. 27.
    Eoss, C. A. C., E. J. Stott, S. McMichael, andI. A. Crowther: Problems of laboratory diagnosis of respiratory syncytial virus infection in childhood. Arch. ges. Virusforsch.14, 553–562 (1964).CrossRefGoogle Scholar
  28. 28.
    Thomason, B. M., andG. S. Cowart: Evaluation of polyvinyl alcohols as semipermanent mountants for fluorescent-antibody studies. J. Bact.93, 768–769 (1967).PubMedPubMedCentralGoogle Scholar
  29. 29.
    Ver, B. A., J. L. Melnick, andC. Wallis: Efficient filtration and sizing of viruses with membrane filters. J. Virol.2, 21–25 (1968).PubMedPubMedCentralGoogle Scholar
  30. 30.
    Waterson, A. P., andD. Hobson: Relationship between respiratory syncytial virus and Newcastle disease-parainfluenza group. Brit. med. J.ii, 1166–1167 (1962).CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1970

Authors and Affiliations

  • M. F. Paccaud
    • 1
  • Cl. Jacquier
    • 1
  1. 1.Section de Virologie, Service de Microbiologie MédicaleInstitut d'HygièneGenevaSwitzerland

Personalised recommendations