Journal of Neural Transmission

, Volume 37, Issue 1, pp 25–32 | Cite as

Failure of decreased serotonin uptake or monoamine oxidase inhibition to block the acceleration in brain 5-hydroxyindole synthesis that follows food consumption

  • J. H. Jacoby
  • J. L. Colmenares
  • R. J. Wurtman
Article
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Summary

The acceleration in brain serotonin synthesis produced by injecting rats with tryptophan or allowing them to consume a carbohydrate diet was not blocked by the prior elevation of brain serotonin levels (by administration of a MAO inhibitor: Lilly 516411) or by a treatment (chlorimipramine administration) that decreases impulse flow along serotoninergic neurons.

Keywords

Serotonin Tryptophan Monoamine Food Consumption Monoamine Oxidase 
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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • J. H. Jacoby
    • 1
  • J. L. Colmenares
    • 1
  • R. J. Wurtman
    • 1
  1. 1.Laboratory of Neuroendocrine Regulation, Department of Nutrition and Food ScienceMassachusetts Institute of TechnologyCambridgeUSA

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