The effect of prostaglandin E1 on free fatty acid mobilization and transport
Contributed Papers I. Phenomena of Membrane Physiology Part C Transport and Drugs
- 17 Downloads
- 1 Citations
Summary
Prostaglandin E1 (administered by intravenous infusion at the dosis of 5.6μg/kg/min.) (markedly decreases plasma free fatty acids in Sprague-Dawley rats treated with ACTH or norepinephrine or exposed to cold.
The blocking effect is absent in fasted animals, indicating a specific effect of PGE1 on the hormone-activated lipase.
Keywords
Lipase Prostaglandin Free Fatty Acid Norepinephrine PGE1
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- [1]Von Euler, U. S., 1934: Arch. Exper. Path. Pharm.175, 78.Google Scholar
- [2]—, 1939: Skand. Arch. Physiol.81, 65.Google Scholar
- [3]Bergström, S., R. Ryhage, B. Samuelsson, and J. Sjövall, 1962: Acta Chem. Scand.16, 501.Google Scholar
- [4]—, F. Dressler, R. Ryhage, B. Samuelsson, and J. Sjövall, 1962: Arkiv. Kemi19, 565.Google Scholar
- [5]Samuelsson, B., 1965: Angewandte Chemie77, 445.Google Scholar
- [6]Horton, E. W., 1965: Experientia21, 113.Google Scholar
- [7]Eliansson, R., 1963: Biochem. Pharm.12, 405.Google Scholar
- [8]Horton, E. W., and H. M. Main, 1963: Brit. J. Pharm.21, 192.Google Scholar
- [9]Steinberg, D., M. Vaughan, P. J. Nestel, O. Strand, and S. Bergström, 1964: J. Clin. Invest.43, 1533.Google Scholar
- [10]Bergström, S., 1965: J. Amer. Oil Chem. Soc.42, 608.Google Scholar
- [11]Berti, F., and M. M. Usardi, 1964: Giorn. It. Ateroscl.2, 261.Google Scholar
- [12]Unpublished data.Google Scholar
- [13]Samuelsson, B., 1964: J. Biol. Chem.239, 4091.Google Scholar
- [14]Bergström, S., L. A. Carlson, and L. Öro, 1963: Biochem. J.89, 278.Google Scholar
- [15]— — — 1964: Acta Physiol. Scand.60, 170.Google Scholar
- [16]Steinberg, D., M. Vaughan, P. J. Nestel, and S. Bergström, 1963: Biochem. Pharm.12, 764.Google Scholar
- [17]Berti, F., R. Lentati, and M. M. Usardi, 1965: Boll. Soc. It. Biol. Sper. (in press).Google Scholar
- [18]- - - 1965: Giorn. It. Ateroscl. (in press).Google Scholar
- [19]Bergström, S., L. A. Carlson, L. G. Ekelund, and L. Öro, 1965: Proc. Soc. Exper. Biol. Med.118, 110.Google Scholar
- [20]Stern, D. C., and R. P. Maickel, 1963: Life Sciences2, 872.Google Scholar
- [21]Carlson, L. A., 1965: Proceedings of the 2nd International Symposium on Drugs Affecting Lipid Metabolism, Milan, September.Google Scholar
- [22]—, 1963: Acta Med. Scand.173, 719.Google Scholar
- [23]Vertua, R., M. M. Usardi, R. Bombelli, T. Farkas, and R. Paoletti, 1964: Life Sciences3, 281.Google Scholar
- [24]Farkas, T., R. Vertua, M. M. Usardi, and R. Paoletti, 1964: Life Sciences3, 821.Google Scholar
- [25]Nikkilä, E. A., and A. Hyvärinen, 1962: Clin. Chim. Acta7, 140.Google Scholar
- [26]Dole, V. P., 1956: J. Clin. Invest.35, 150.Google Scholar
Copyright information
© Springer-Verlag 1967