Archiv für die gesamte Virusforschung

, Volume 25, Issue 1, pp 38–51 | Cite as

Characterization of a small Porcine DNA virus

  • A. Mayr
  • P. A. Bachmann
  • G. Siegl
  • H. Mahnel
  • B. E. Sheffy


Characteristics of a small DNA virus isolated from kidney cell cultures of healthy 3 week-old pigs are described.

The virus isolate multiplies in kidney cell cultures of pig origin, produces intranuclear inclusion bodies, and hemagglutinates guinea pig, human group 0, chicken, cat, rat and mouse red blood cells. It multiplies in pigs resulting in antibody production, but is not pathogenic for newborn hamsters and mice.

The virus particle is 20–22 mμ in size, hexagonal in shape and without a lipid containing envelope. Buoyant density is between 1.37 and 1.38g/ml. This virus is stable within a wide range of pH, resistant to heat (56°C), against treatment with trypsin, and lipid solvents.

The porcine virus was proposed as a member of the picodna virus group, and named “Porcine Picodna Virus (PPV)”.


Virus Particle Inclusion Body Virus Isolate Human Group Intranuclear Inclusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Archetti, I., eD. Steve-Bocciarelli: Ann. Ist. Super. Sanità1, 103 (1965).Google Scholar
  2. 2.
    Atchinson, R. W., B. C. Casto, andW. Hammon: Science149, 754 (1965).Google Scholar
  3. 3.
    Bachmann, P. A.: In press.Google Scholar
  4. 4.
    Black, F. L.: Virology5, 391 (1958).Google Scholar
  5. 5.
    Cartwright, S. F., andR. A. Huck: Vet. Rec.81, 196 (1967).Google Scholar
  6. 6.
    Crawford, L. V.: Virology29, 605 (1966).Google Scholar
  7. 7.
    Dinter, Z.: Zbl. Bakt. I. Abt. Orig.188, 475 (1963).Google Scholar
  8. 8.
    Greene, E. L.: Proc. Soc. exp. Biol. (N.Y.)118, 973 (1965).Google Scholar
  9. 9.
    Hallauer, C.: Personal communication.Google Scholar
  10. 10.
    Hoggan, M. D., N. R. Blacklow, andW. P. Rowe: Proc. nat. Acad. Sci. (Wash.)55, 1467 (1966).Google Scholar
  11. 11.
    Horzinek, M., M. Mussgay, J. Maess undK. Petzoldt: Arch. ges. Virusforsch.21, 98 (1967).Google Scholar
  12. 12.
    Kilham, L., andJ. L. Olivier: Virology7, 437 (1959).Google Scholar
  13. 13.
    Kilham, L.: Virology13, 141 (1961).Google Scholar
  14. 14.
    Mayor, H. D., andA. R. Diwan: Virology14, 74 (1961).Google Scholar
  15. 15.
    Mayor, H. D., R. M. Jamison, L. E. Jordan, andJ. L. Melnick: J. Bact.90, 235 (1965).Google Scholar
  16. 16.
    Mayor, H. D., andJ. L. Melnick: Nature (Lond.)210, 331 (1966).Google Scholar
  17. 17.
    Mayr, A.: Arch. ges. Virusforsch.6, 439 (1956).Google Scholar
  18. 18.
    Mayr, A., undK. Bögel: Zbl. Bakt. I. Abt. Orig.182, 564 (1961).Google Scholar
  19. 19.
    Mayr, A., undH. Mahnel: Zbl. Bakt. I. Abt. Orig.195, 157 (1964).Google Scholar
  20. 20.
    Mayr, A., undH. Mahnel: Zbl. Bakt. I. Abt. Orig.199, 399 (1966).Google Scholar
  21. 21.
    Mayr, A., P. A. Bachmann, B. E. Sheffy undG. Siegl: Arch. ges. Virusforsch.21, 113 (1967).Google Scholar
  22. 22.
    Melnick, J. L., H. D. Mayor, K. L. Smith, andJ. Rapp: J. Bact.90, 271 (1965).Google Scholar
  23. 23.
    Moore, A. E.: Virology18, 182 (1962).Google Scholar
  24. 24.
    Payne, F., T. F. Beals, andR. E. Preston: Virology23, 109 (1964).Google Scholar
  25. 25.
    Schwöbel, W., undE. Traub: Mh. Tierheilk.11, 15 (1959).Google Scholar
  26. 26.
    Sheffy, B. E.: Proc. Ann. Meet. U.S. Livestock San. Ass.69, 351 (1965).Google Scholar
  27. 27.
    Smith, K. L., W. D. Gehle, andJ. F. Thiel: J. Immunol.97, 754 (1966).Google Scholar
  28. 28.
    Toolan, H. W., G. Dalldorf, M. Barclay, S. Chandra, andA. E. Moore: Proc. nat. Acad. Sci. (Wash.)46, 1256 (1960).Google Scholar
  29. 29.
    Toolan, H. W.: Proc. Amer. Ass. Cancer Res.5, 64 (1964).Google Scholar
  30. 30.
    Toolan, H. W.: Proc. Soc. exp. Biol. (N.Y.)124, 144 (1967).Google Scholar
  31. 31.
    Vasquez, C., andC. Brailowsky: Exp. molec. Path.4, 130 (1965).Google Scholar

Copyright information

© Springer-Verlag 1968

Authors and Affiliations

  • A. Mayr
    • 1
  • P. A. Bachmann
    • 1
  • G. Siegl
    • 1
  • H. Mahnel
    • 1
  • B. E. Sheffy
    • 1
  1. 1.Institut für Mikrobiologie und Infektionskrankheiten der Tiere der Universität MünchenDeutschland

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