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Somatic Cell and Molecular Genetics

, Volume 18, Issue 2, pp 189–194 | Cite as

Mapping of the humanGSPT1 gene, a human homolog of the yeastGST1 gene, to chromosomal band 16p13.1

  • Kazuo Ozawa
  • Yasufumi Murakami
  • Toshihiko Eki
  • Kazushige Yokoyama
  • Eiichi Soeda
  • Shin-ichi Hoshino
  • Michio Ui
  • Fumio Hanaoka
Brief Communication

Abstract

TheGSPT1 gene, a human homolog of the yeastGST1 gene (formerly namedGST1-Hs), was mapped on human chromosome 16p13.1 by a combination of nonradioactive in situ hybridization and Giemsa staining. Southern blot hybridization with a panel of human-rodent somatic cells confirmed the location of theGSPT1 gene on chromosome 16 and also showed the existence of a homologous gene on the X chromosome. A breakpoint for nonrandom chromosome rearrangements has been found in the region ofGSPT1 in patients with acute nonlymphocytic leukemia.

Keywords

Leukemia Somatic Cell Southern Blot Human Chromosome Homologous Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • Kazuo Ozawa
    • 1
  • Yasufumi Murakami
    • 1
  • Toshihiko Eki
    • 1
  • Kazushige Yokoyama
    • 1
    • 2
  • Eiichi Soeda
    • 1
  • Shin-ichi Hoshino
    • 3
  • Michio Ui
    • 3
  • Fumio Hanaoka
    • 4
  1. 1.Gene BankRiken InstituteIbarakiJapan
  2. 2.Frontier Research ProgramRiken InstituteIbarakiJapan
  3. 3.Department of Physiological Chemistry, Faculty of Pharmaceutical SciencesUniversity of TokyoTokyoJapan
  4. 4.Cellular Physiology LaboratoryRiken InstituteSaitamaJapan

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