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International Journal of Biometeorology

, Volume 37, Issue 3, pp 133–138 | Cite as

Electromagnetic wave emitting products and “Kikoh” potentiate human leukocyte functions

  • Yukie Niwa
  • Osamu Iizawa
  • Koichi Ishimoto
  • Xiaoxia Jiang
  • Tadashi Kanoh
Original articles

Abstract

Tourmaline (electric stone, a type of granite stone), common granite stone, ceramic disks, hot spring water and human palmar energy (called “Kikoh” in Japan and China), all which emit electromagnetic radiation in the far infrared region (wavelength 4–14 µm). These materials were thus examined for effects on human leukocyte activity and on lipid peroxidation of unsaturated fatty acids. It was revealed that these materials significantly increased intracellular calcium ion concentration, phagocytosis, and generation of reactive oxygen species in neutrophils, and the blastogenetic response of lymphocytes to mitogens. Chemotactic activity by neutrophils was also enhanced by exposure to tourmaline and the palm of “Kikohshi” i.e., a person who heals professionally by the laying on of hands. Despite the increase in reactive oxygen species generated by neutrophils, lipid peroxidation from unsaturated fatty acid was markedly inhibited by these four materials. The results suggest that materials emitting electromagnetic radiation in the far infrared range, which are widely used in Japan for cosmetic, therapeutic, and preservative purposes, appear capable of potentiating leukocyte functions without promoting oxidative injury.

Key words

Calcium concentration Electromagnetic wave Human palmar energy (Kikoh) Leukocyte function 

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References

  1. Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911–917PubMedGoogle Scholar
  2. Goto N (1990) What is the electro-magnetic wave? — to see the invisible waves. (in Japanese) Kohdansha, TokyoGoogle Scholar
  3. Honda K, Inoue S (1988) Sleep-enhancing effects of far-infrared radiation. Int J Biometeorol 32:92–94PubMedGoogle Scholar
  4. Inoue S, Honda K (1986) Growth of rats exposed to far-infrared radiation. Zool Sci 3:731–732Google Scholar
  5. Inoue S, Kabaya M (1989) Biological activities caused by far-infrared radiation. Int J Biometeorol 33:145–150PubMedGoogle Scholar
  6. Inoue S, Kimura-Takeuchi M, Honda K (1990) Co-circulating sleep substances interactingly modulate sleep and wakefulness in rats. Endocrinol Exp 24:69–76PubMedGoogle Scholar
  7. Ise N, Katsuura T, Kikuchi Y, Miwa E (1987) Effect of far-infrared radiation on forearm skin blood flow. Ann Physiol Anthrop 6:31–32PubMedGoogle Scholar
  8. Johnston RJ Jr, Lehmeyer JE (1976) Elaboration of toxic oxygen by-products by neutrophils in a model of immune complex diseases. J Clin Invest 57:836–841PubMedGoogle Scholar
  9. Klebanoff SJ, Rosen H (1978) Ethylene formation by polymorphonuclear leukocytes. J Exp Med 148:490–505PubMedGoogle Scholar
  10. Lee SP, Honda K, Rhee YH, Inoue S (1990) Chronic intake ofPanax ginseng extract stabilizes sleep and wakefulness in food-deprived rats. Neurosci Lett 111:217–221PubMedGoogle Scholar
  11. Massay V (1959) The microestimation of succinate and the extinction coefficient of cytochrome c. Biochim Biophys Acta 34:255–256PubMedGoogle Scholar
  12. Matsushita K (1990) Water examined with nuclear magnetic resonance (NMR). (in Japanese) Sunload, TokyoGoogle Scholar
  13. Nelson RD, Quie PG, Simmons RL (1977) Chemotaxis under agarose. A new and simple method for measuring chemotaxis and sponaneous migration of human polymorphonuclear leukocytes and monocytes. J Immunol 115:1650–1656Google Scholar
  14. Nishigaki I, Hagihara M, Hiramatsu M, Izawa Y, Yagi K (1980) Effect of thermal injury of lipid peroxide levels of rat. Biochem Med 24:185–189PubMedGoogle Scholar
  15. Nishizuka Y (1989) Studies and prospectives of the protein kinase C family for cellular regulation. Cancer 63:1892–1903PubMedGoogle Scholar
  16. Niwa Y, Kanoh T (1979) Immunological behaviour following rubella infection. Clin Exp Immunol 37:470–476PubMedGoogle Scholar
  17. Niwa Y, Komuro T (1991a) The effect of far infrared ray emitting platinum electro-magnetic wave fiber on the activities of normal human neutrophils and myelotic leukemia cell lines, and the growth of malignant tumors. In: Carpi A, Sagripanti A, Grassi B (eds) Advances in management of malignancies. Monduzzi Editore, Bologna, Italy, pp 21–27Google Scholar
  18. Niwa Y, Komuro T (1991b) Effect of electric instruments and human palmar energy on healthy and diseased individuals. (in Japanese) Jpn J Inflammation 11:135–141Google Scholar
  19. Niwa Y, Taniguchi S (1986) Phospholipid base exchange in human leukocyte membranes: quantitation and correlation with other phospholipid biosynthetic pathways. Arch Biochem Biophys 250:345–357PubMedGoogle Scholar
  20. Niwa Y, Sakane T, Shingu M, Yanagida I, Komura J, Miyachi Y (1985) Neutrophil-generated active oxygens in linear IgA bullous dermatosis. Arch Dermatol 121:73–78PubMedGoogle Scholar
  21. Niwa Y, Kanoh T, Kasama T, Negishi M (1988a) Activation of antioxidant activity in natural medicinal products by heating, brewing, and lipophilization. A new drug delivery system. Drugs Exp Clin Res 14:361–372PubMedGoogle Scholar
  22. Niwa Y, Miyachi Y, Sakane T, Kanoh T, Taniguchi S (1988b) Methyltransferase and phospholipase A2 activity in the cell membrane of neutrophils and lymphocytes from patients with Behçet's disease, systemic lupus erythematosus, and rheumatoid arthritis. Clin Chim Acta 174:1–14PubMedGoogle Scholar
  23. Niwa Y, Kasama T, Miyachi Y, Kanoh T (1989) Neutrophil chemotaxis, phagocytosis and parameters of reactive oxygen species in human aging: cross-sectional and longitudinal studies. Life Sci 44:1655–1664PubMedGoogle Scholar
  24. Ozaki Y, Kume S (1988) Functional responses of aequorin-loaded human neutrophils. Comparison with fura-2-loaded cell. Biochim Biophys Acta 972:113–119PubMedGoogle Scholar
  25. Root RK, Metcalf JA (1972) H2O2 release from human granulocytes during phagocytosis. J Clin Invest 60:1266–1279Google Scholar
  26. Stossel TP (1973) Evaluation of opsonic and leukocyte function with a spectrophotometric test in patients with infection and with phagocytic disorders. Blood 42:121–130PubMedGoogle Scholar
  27. Welsch CW (1987) Enhancement of mammary tumorigenesis by dietary fat: review of potential mechanisms. Am J Clin Nutr 45:192–202PubMedGoogle Scholar
  28. Wolken JJ (1971) Invertebrate photoreceptors — a comparative analysis. Academic Press, New YorkGoogle Scholar
  29. Wolken JJ (1975) Photoprocesses, photoreceptors, and evolution. Academic Press, New York, pp 1–25Google Scholar
  30. Yagi K (1984) Increased serum lipid peroxides initiate atherogenesis. Bio Essays 1:58–60Google Scholar

Copyright information

© International Society of Biometeorology 1993

Authors and Affiliations

  • Yukie Niwa
    • 1
  • Osamu Iizawa
    • 2
  • Koichi Ishimoto
    • 3
  • Xiaoxia Jiang
    • 1
  • Tadashi Kanoh
    • 4
  1. 1.Niwa Institute for ImmunologyTosashimizu, Kochi-kenJapan
  2. 2.Department of DermatologyTohoku University School of MedicineSendaiJapan
  3. 3.Department of Pediatrics, Faculty of MedicineJuntendo UniversityJapan
  4. 4.Department of Internal Medicine, Faculty of MedicineKyoto UniversityJapan

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