Journal of Cancer Research and Clinical Oncology

, Volume 118, Issue 8, pp 621–625 | Cite as

Tobacco-related cancer in relation to prevalence of drinking and smoking in Eastern Austria

  • Herwig Swoboda
  • Hans-Peter Friedl
Original Papers Clinical Oncology
Received:
Accepted:

Summary

Eastern Austrian regional mortality patterns of oral cancer (oral cavity, pharynx and larynx) and oesophageal, lung and urinary bladder cancer were compared to smoker rates and to liver cirrhosis mortality by type of residence: Vienna (1.7×106 inhabitants), middle towns (50 000–100 000 and 10 000–50 000 inhabitants), small towns (2000–10 000 inhabitants) and rural areas categorized by agrarian quota ≦10%, 10%–20% and >20%. The study area (Vienna, Lower Austria and Burgenland) covers 23 600 km2 with 3.23×106 inhabitants. In men, liver cirrhosis correlated negatively with smoker rates (r=−0.74, P=0.1). Deaths from oral cancer and oesophageal cancer correlated significantly with deaths from liver cirrhosis (r=0.81, P=0.03; r=0.78, P=0.04, respectively) but not with smoker rates; lung cancer and bladder cancer correlated significantly with smoker rates (r=0.91, P=0.01; r0.83, P=0.04, respectively), but not with liver cirrhosis. In women, similar urban-rural gradients for all parameters resulted in a positive correlation between liver cirrhosis and smoker rates (r=0.59, P=0.22) and a significant correlation of lung cancer with liver cirrhosis (r=0.75, P=0.05). Oral cancer correlated significantly with liver cirrhosis (r=0.83, P=0.02), but not with smoker rates; lung cancer correlated more significantly with smoker rates (r=0.92, P=0.01) than with liver cirrhosis; bladder cancer correlated positively with smoker rates (r=0.70, P=0.12). Geographical distribution of oral and oesophageal cancer in Eastern Austria seems thus to be highly subject to the prevalence of heavy drinking. Sociocultural influences upon the occurrence of these cancers seem to be mediated through drinking habits rather than through smoking habits alone.

Key words

Cancer Epidemiology Liver cirrhosis Alcohol Tobacco 
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References

  1. Austrian Central Statistical Office (1989) Österreichischer Todesursachenatlas 1978/84, Österr. Staatsdruckerei, WienGoogle Scholar
  2. Brugère J, Guenel P, Leclerc A, Rodriguez J (1986) Differential effects of tobacco and alcohol in cancer of the larynx, pharynx and mouth. Cancer 57:391–395Google Scholar
  3. Elwood JM, Pearson JCG, Skippen DH, Jackson SM (1984) Alcohol, smoking, social and occupational factors in the aetiology of cancer of the oral cavity, pharynx and larynx. Int J Cancer 34:603–612Google Scholar
  4. Friedl H-P (1987a) Rauchgewohnheiten der österreichischen Bevölkerung. Stat Nachr 42:328–332Google Scholar
  5. Friedl H-P (1987b) Regionale Aspekte des Rauchens. Stat Nachr 42:396–397Google Scholar
  6. Hakulinen T, Andersen Aa, Malker B, Pukkala E, Schou G, Tulinius H (1986) Trends in cancer incidence in the nordic countries. A collaborative study of the five Nordic Cancer Registries. The Nordic Cancer Registries, HelsinkiGoogle Scholar
  7. Jensen OM (1991) International variation in the incidence of cancer of the upper digestive and respiratory tract. Adv Otorhinolaryngol 46:124–133Google Scholar
  8. La Vecchia C, Boyle P, Franceschi S, Levi F, Maisonneuve P, Negri E, Lucchini F, Smans M (1991) Smoking and cancer with emphasis on Europe.. Eur J Cancer 27:94–104Google Scholar
  9. Lesch OM (1985) Chronischer Alkoholimus. Tpyen und Verlauf. Eine Langzeitstudie. Thieme, StuttgartGoogle Scholar
  10. Luce D, Guenel P, Leclerc A, Brugère J, Point D, Rodriguez J (1988) Alcohol and tobacco consumption in cancer of the mouth, pharynx and larynx: a study of 316 female patients. Laryngoscope 98:313–316Google Scholar
  11. Mader R, Mittendorfer Ch, Pavlis L, Springer A (1981) Österreichische Trinksitten. Konsumation—Einstellung Gefährdung. Schriftenreihe des Ludwig-Boltzmann-Institutes für Suchtforschung, vol 4. Brüder Hollinek, Wien, p 39Google Scholar
  12. Neumann G (1988) Bösartige Neubildungen von Lippe, Mundhöhle, Rachen, Nase, Ohr und Kehlkopf. Eine deskriptiv-epidemiologische Untersuchung. HNO 36:345–354Google Scholar
  13. Schwartz D, Flamant R, Lellouch J, Denoix P (1961) Results of a French survey on the role of tobacco, particularly inhalation, in different cancer sites. J Natl Cancer Inst 29:1085–1108Google Scholar
  14. Schwartz D, Lellouch J, Flamant R, Denoix P (1962) Alcohol et cancer. Résultats d'une enquête rétrospective. Rev Fr Etud Clin Biol 7:590–604Google Scholar
  15. Swoboda H (1991) Epidemiology of head and neck cancer in Eastern Austria. Adv. Otorhinolaryngol 46:134–144Google Scholar
  16. Swoboda H, Friedl H-P (1991) Incidence of cancer of the respiratory and upper digestive tract in urban and rural Eastern Austria. Eur J Cancer 27:83–85Google Scholar
  17. Swoboda H, Neumann H, Cartellieri M (1990) Zur Epidemiologie bösartiger Neubildungen des Atmungs-und oberen Verdauungstraktes in Österreich. Laryngol Rhinol Otol (Stuttg) 69:123–130Google Scholar
  18. Tuyns A (1991) Aetiology of head and neck cancer: tobacco, alcohol and diet. Adv Otorhinolaryngol 46:98–106Google Scholar
  19. Tuyns AJ, Estève J, Raymond L, Berrino F, Benhamou E, Blanchet F, Boffetta P, Crosignani P, Del Moral A, Lehmann W, Merletti F, Péquinot G, Riboli E, Sancho-Garnier H, Terracini B, Zubiri A, Zubiri L (1988) Cancer of the larynx/hypopharynx, tobacco and alcohol: IARC international case-control study. Int J Cancer 41:483–491Google Scholar
  20. Wynder EL, Bross IJ (1957) Aetiological factors in mouth cancer. Br Med J 1:1137–1171Google Scholar

Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Herwig Swoboda
    • 1
  • Hans-Peter Friedl
    • 2
  1. 1.Department of Otorhinolaryngology 1University of ViennaViennaAustria
  2. 2.Austrian Central Statistical OfficeViennaAustria

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