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Comparison of pregnancy rates following in vitro fertilization—embryo transfer between the donors and the recipients in a donor oocyte program

  • Jerome H. Check
  • Kosrow Nowroozi
  • Jeffrey Chase
  • Ahmad Nazari
  • Carolyn Braithwaite
Clinical Assisted Reproduction

Abstract

Our in vitro fertilization (IVF) program provides a unique opportunity to evaluate influences of hormonal milieu on pregnancy outcome, by using a shared pool of oocytes obtained by donors (in exchange for financial assistance). The study presented herein evaluated 38 retrieval cycles (28 oocyte donors/22 recipients). No difference in mean number of embryos transferred was seen (2.7 in the donors vs 2.8 in the recipients). However, a statistically significant difference was seen in the pregnancy rates per retrieval (10.5% donors vs 29% recipients) and per transfer (4/35, 11.1%, vs 11/34, 32.3%). Abortion rates were similar (25% donor, 27.2% recipients). These data suggest that other reports of higher pregnancy rates from donor oocyte programs may not be due exclusively to better-quality oocytes. Possibly a negative effect of hyperstimulation or adverse endometrial environment of the donor (possible chronic endometritis) may explain these data.

Key words

donor oocyte recipients hyperstimulation regimen pregnancy rates 

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References

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Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • Jerome H. Check
    • 1
    • 2
  • Kosrow Nowroozi
    • 1
    • 2
  • Jeffrey Chase
    • 1
    • 2
  • Ahmad Nazari
    • 1
    • 2
  • Carolyn Braithwaite
    • 2
  1. 1.Department Ob/Gyn, Division of Reproductive Endocrinology and InfertilityThe UMDNJ, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical CenterCamdenUSA
  2. 2.Endocrine Histology AssociatesMelrose ParkUSA

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