UV radiation ocular exposure dosimetry

  • David H. Sliney


Cataractogenesis by ultraviolet radiation (UVR) has been shown convincingly by a host of different laboratory studies. However, crucial epidemiological evidence linking chronic UVR exposure to age-related cataract appears to be lacking, since different environmental studies have led to apparently conflicting results. This paper explores a possible explanation for these conflicting results: errors in dosimetry. Any epidemiological study depends upon good dosimetry of the subjects' exposures. A careful examination of the biophysical, physiological and behavioral factors which determine the level of UVR exposure of the lens reveals a number of surprises which should explain the apparently conflicting epidemiological results. It is shown that geometrical and behavioral factors related to sunlight are so important, that by overlooking these factors, past epidemiological studies of UVR and cataract could readily be expected to produce conflicting results.

Key words

Ultraviolet irradiation Lens Ultraviolet dosimetry Ultraviolet measurement Eye protection 


  1. 1.
    Sliney DH. Eye protective techniques for bright light. Ophthalmology 1983; 90: 937–44.PubMedGoogle Scholar
  2. 2.
    Sliney D. Physical factors in cataractogenesis: ambient ultraviolet radiation and temperature. Invest Ophthalmol Vis Sci 1986; 27: 781–90.PubMedGoogle Scholar
  3. 3.
    Sliney D. Estimating the solar ultraviolet radiation exposure to an intraocular lens implant. J Cataract Refract Surg 1987; 13: 296–301.PubMedGoogle Scholar
  4. 4.
    Sliney DH, Wolbarsht ML. Safety with lasers and other optical sources. New York: Plenum Publishing Corp., 1980.Google Scholar
  5. 5.
    Rosenthal F, Phoon C, Bakalian A, Taylor H. The ocular dose of ultraviolet radiation to outdoor workers. Invest Ophthalmol Vis Sci 1988; 29: 649–56.PubMedGoogle Scholar
  6. 6.
    Rosenthal F, Safran M, Taylor H. The ocular dose of ultraviolet radiation from sunlight exposure. Photochem Photobiol 1985; 42: 163–71.PubMedCrossRefGoogle Scholar
  7. 7.
    Henderson ST. Daylight and its spectrum. New York: American Elsevier Publishing Co., 1970.Google Scholar
  8. 8.
    Kostkowski HJ, Saunders RD, Ward JF, Popenoe CH, Green AES. Measurements of solar terrestrial spectral irradiance in the ozone cut-off region. Self-study manual on optical radiation measurements. Part III, Applications, Chapter 1. NBS Technical Note 910-5. Washington, DC: National Bureau of Standards, 1982.Google Scholar
  9. 9.
    Scotto J, Fears TR, Gori GB. Measurements of ultraviolet radiations in the United States and comparisons with skin cancer data. U.S. Department of Health, Education and Welfare Publication No. (NIH)80-2154, 1980.Google Scholar
  10. 10.
    Garrison LM, Murray LE, Doda DD, Green, AES. Diffuse-direct ultraviolet ratios with a compact double monochromator. Appl Opt, 1978; 17: 827–35.CrossRefGoogle Scholar
  11. 11.
    Doda, DD, Green, AES. Surface reflectance measurements in the UV from an airborne platform. Part 1. Appl Optics 1980; 19: 2140–45.CrossRefGoogle Scholar
  12. 12.
    Sliney DH, Wood RL, Moscato PM, Marshall WJ, Eriksen P. Ultraviolet exposure in the outdoor environment. In: Grandolfo M, Rindi A, Sliney D, eds. Light, lasers and synchrotron radiation — A health risk assessment. New York: Plenum Press, 1990: 169–80.Google Scholar
  13. 13.
    Kromann N, Wulf HC, Eriksen P, Brodthagen H. Relative ultraviolet spectral intensity of direct solar radiation, sky radiation and surface reflections. Photodermatology 1986; 3: 73–82.PubMedGoogle Scholar
  14. 14.
    Livingston W. The landscape as viewed in the 320 nm ultraviolet. J Opt Soc Am 1983; 73: 1653–58.CrossRefGoogle Scholar
  15. 15.
    Hedblom EE. Snowscape eye protection. Arch Environ Health 1961; 2: 685–704.PubMedGoogle Scholar
  16. 16.
    Chatterjee J. Cataract in Punjab. In: The human lens in relation to cataract. Amsterdam: Elsevier, 1973: 265–79.CrossRefGoogle Scholar
  17. 17.
    Brilliant LB, Grasset NC, Pokherl RP. Associations among cataract prevalence, sunlight hours, and altitude in the Himalayas. Am J Epidemiol 1983; 118: 250–64.PubMedGoogle Scholar
  18. 18.
    Taylor HR, West SK, Rosenthal FS. Effect of ultraviolet radiation on cataract formation. N Engl J Med 1988; 319: 1429–33.PubMedGoogle Scholar
  19. 19.
    Parrish JA, Anderson RR, Urbach F, Pitts DG. UV-A, biological effects of ultraviolet radiation with emphasis on human responses to long wave ultraviolet. New York: Plenum Press, 1978.Google Scholar
  20. 20.
    Pitts DG, Cullen AP, Hacker PD. Ocular effects of ultraviolet radiation from 295 to 365 nm. Invest Ophthalmol Vis Sci 197; 16: 932–9.Google Scholar
  21. 21.
    Zuclich JA, Connolly JS. Ocular damage induced by near ultraviolet laser radiation. Invest Ophthalmol 1976; 15: 760–64.Google Scholar
  22. 22.
    American Conference of Governmental Industrial Hygienists. TLVs, Threshold Limit Values for chemical substances and physical agents in the work environment and biological exposure indices with intended changes for 1993–1994. Cincinnati, ACGIH, 1993.Google Scholar
  23. 23.
    American Conference of Governmental Industrial Hygienists. Documentation of the Threshold Limit Values. 6th Edn. Cincinnati, ACGIH, 1992: 451–55.Google Scholar
  24. 24.
    Sliney DH. The merits of an envelope action spectrum for ultraviolet radiation exposure criteria. Amer Industr Hyg Assn J 1972; 33: 644–43.CrossRefGoogle Scholar
  25. 25.
    Coroneo MT. Albedo concentration in the anterior eye: a phenomenon that locates some solar diseases. Ophthalmic Surg 1990; 21: 60–66.PubMedGoogle Scholar
  26. 26.
    Coroneo MT, Müller-Stolzenburg NW, Ho A. Peripheral light focussing by the anterior eye and the ophthalmohelioses. Ophthalmic Surg 1991; 22: 705–11.PubMedGoogle Scholar
  27. 27.
    Coroneo MT. Pterygeum as an early indicator of ultraviolet insolation: an hypothesis. Br J Ophthalmol 1993; 77: 734–39.PubMedCrossRefGoogle Scholar
  28. 28.
    Maloof AJ, Ho A, Coroneo MT. Anterior segment peripheral light focussing: effect of incident angles and corneal shape. Invest Ophthalmol Vis Sci 1993; 34.Google Scholar
  29. 29.
    Klein BEK, Klein R, Linton KLP. Prevalence of age-related lens opacities in a population, the Beaver Dam eye study. Ophthalmology 1992; 99: 546–52.PubMedGoogle Scholar
  30. 30.
    Cruickshanks KJ, Klein BEK, Klein R. Ultraviolet light exposure and lens opacities: the Beaver Dam eye study. Am J Publ Health 1992; 82: 1658–62.CrossRefGoogle Scholar
  31. 31.
    Dillon J, Garner MH, Roy D, Spector A. The photolysis of lens proteins: molecular changes. Exp Eye Res 1982; 34: 651–58.PubMedCrossRefGoogle Scholar
  32. 32.
    Giese AC. Living with our sun's ultraviolet rays. New York: Plenum Press, 1976.Google Scholar

Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • David H. Sliney
    • 1
  1. 1.Laser Microwave DivisionUS Army Environmental Hygiene AgencyAberdeen Proving GroundUSA

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