Long-term results of surgery for small primary liver cancer in 514 adults
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During 1958–1993, 2030 patients with pathologically proven primary liver cancer (PLC) were retrospectively reviewed. Comparison between small PLC (<-5 cm,n=514) and large PLC (>5 cm,n=1516) revealed that small PLC had a higher resection rate (92.4% versus 49.1%), lower operative mortality (1.7% versus 5.2%), a higher percentage of single tumour nodules (78.0% versus 53.4%), a higher percentage of well encapsulated tumour (74.5% versus 35.8%) and higher survival rates after resection (5-year, 63.8% versus 36.6%; 10-year, 46.8% versus 28.5%). No significant difference was found between survival following limited resection (n=440) and lobectomy (n=34) in patients with small PLC. Re-resection of any subclinical recurrence or solitary pulmonary metastasis after small PLC resection was done in 70 cases. These results indicate that resection is still the modality of choice for treatment of small PLC; limited resection instead of lobectomy was the key to increasing resectability and decreasing operative mortality; re-resection of subclinical recurrence was important to prolong survival further.
Key wordsHepatoma Resection Prognosis
primary liver cancer
hepatitis B surface antigen
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- Zhou XD (1994) Advances in primary liver cancer research. Chin J Cancer Res 6:1–2Google Scholar
- Zhu YR, Lu BX (1983) Clinical implication of AFP serosurvey. Chin J Oncol 5:38–40Google Scholar
- Zhou XD, Tang ZY, Yu YQ (1994a) Decreasing posthepatectomy liver failure. In: Sugarbaker PH (ed) Hepatobiliary cancer. Kluwer Boston, pp 307–312Google Scholar
- Zhou XD, Yu YQ, Tang ZY (1994b) Advances in surgery for hepatocellular carcinoma. Asian J Surg 17:34–39Google Scholar