Microchimica Acta

, Volume 92, Issue 4–6, pp 229–236 | Cite as

Microcoulometric determination of protonation constants of nuphar alkaloids

  • Stanisław Głąb
  • Urszula Nowicka
Original Papers


The coulometric titration technique is applied for evaluation of protonation constants of substances available in micromolar amounts. The validity of the procedure was checked by studying several well-known systems. Unknown constants were evaluated for naturally isolated alkaloids. The advantages of the microcoulometric technique are discussed.

Key words

thiobinupharidine neothiobinupharidine thionuphlutine protonation constants coulometric titrations 


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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • Stanisław Głąb
    • 1
  • Urszula Nowicka
    • 2
  1. 1.Department of ChemistryWarsaw UniversityWarsawPoland
  2. 2.Department of ChemistryUniversity of Teachers CollegeSiedlcePoland

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