Journal of Cancer Research and Clinical Oncology

, Volume 119, Issue 12, pp 700–701 | Cite as

Why does a higher repseonse rate to chemotherapy correlate poorly with improved survival?

  • Maurie Markman
Editorial

References

  1. Cellerino R, Tummarello D, Guidi F, Isidori P, Raspugli M, Biscottini B, Fatati G (1991) A randomized trial of alternating chemotherapy versus best supportive care in advanced non-small-cell lung cancer. J Clin Oncol 9:1453–1461PubMedGoogle Scholar
  2. Cellerino R, Tummarello D, Profiri EM, Guidi F, Isidori P, Raspugli M, Biscottini B, Fatati G (1988) Non small cell lung cancer (NSCLC). A prospective randomized trial with alternating chemotherapy CEP/MEC versus no treatment. Eur J Cancer Clin Oncol 24:1839–1843PubMedGoogle Scholar
  3. Doroshow JH, Multhauf P, Leong L, Margolin K, Litchfield T, Akman S, Carr B, Bertrand M, Goldberg D, Blayney D, Odujinrin O, DeLap R, Shuster J, Newman E (1990) Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy. J Clin Oncol 8:491–501PubMedGoogle Scholar
  4. Ganz PA, Figlin RA, Haskell CM, La Soto N, Siau J (1988) Supportive care versus supportive care and combination chemotherapy in metastatic non-small cell lung cancer. Does chemotherapy make a difference? Cancer 63:1271–1278Google Scholar
  5. Kemeny N, Israel K, Niedzwiecki D, Chapman D, Botet J, Minsky B, Vinciguerra V, Rosenbluth R, Bosselli B, Cochran C, Sheehan K (1990) Randomized study of continuous infusion fluorouracil versus fluorouracil plus cisplatin in patients with metastatic colorectal cancer. J Clin Oncol 8:313–318PubMedGoogle Scholar
  6. Miller AB, Hoogstraten B, Staquet M, Winkler A (1981) Reporting results of cancer treatment. Cancer 47:207–214PubMedGoogle Scholar
  7. Rapp E, Pater JL, Willan A, Cormier Y, Murray N, Evans WK, Hodson DI, Clark DA, Feld R, Arnold AM, Ayoub JI, Wilson KS, Latreille J, Wierzbicki RF, Hill DP (1988) Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer-Report of a Canadian multicenter radomized trial. J Clin Oncol 6:633–641PubMedGoogle Scholar
  8. Woods RL, Williams CJ, Levi J, Page J, Bell D, Byrne M, Kerestes ZL (1989) A randomized trial of cisplatin and vindesine versus supportive care only in advanced non-small cell lung cancer. Brit J Cancer 61:608–611Google Scholar

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Maurie Markman
    • 1
    • 2
  1. 1.Cleveland Clinic Cancer CenterThe Cleveland Clinic FoundationClevelandUSA
  2. 2.the Department of Hematology/Medical OncologyThe Cleveland Clinic FoundationClevelandUSA

Personalised recommendations