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Chromosoma

, Volume 74, Issue 3, pp 347–353 | Cite as

The rate of fork movement during DNA replication in mammalian cells

  • Yu. B. Yurov
Article

Abstract

DNA fiber autoradiography was used to measure the rate of replication fork progression along replication units in human diploid cells. The rate in different replication units differs very significantly and lies within the range 0.1 to 1.2 μm/min. However, no significant changes were found in the rate of fork movement along single replication units operating during long intervals of S phase. Moreover, the fork progression rate is constant in many replication units of human cells.

Keywords

Mammalian Cell Developmental Biology Human Cell Replication Fork Progression Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Yu. B. Yurov
    • 1
  1. 1.Institute of Medical GeneticsAcademy of Medical SciencesMoscowU.S.S.R.

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