Neuroscience and Behavioral Physiology

, Volume 23, Issue 1, pp 49–55 | Cite as

Specific features of the electroretinogram of vertebrates induced by X-rays

  • B. N. Savchenko


The net electroretinograms of dark-adapted retinas of the common frog in situ were investigated on an automated experimental system with programmed control and electronic differentiation of biopotentials with respect to the first and second derivatives. It was demonstrated that X-rays elicit an electroretinogram consisting of two components, provisionally called the first and second X-ray reactions (X-1 and X-2), which differ with respect to their parameters from electroretinograms elicited under the same conditions by red and blue light. The administration of sodium azide, sodium nitrate, monoiodoacetate and other substances alter the X-1 and X-2 as well as the photo-induced ERGs in different ways; this indicates their relative independance and different mechanisms of the occurrence and passing of excitation across the structures of the retina, and makes it possible to partially isolate these for individual study. Thus, the assertion of a number of investigators regarding the absence of specific features in the X-ray induced electroretinograms becomes problematical. The discovery of X-ray-specific reactions in the retina makes it possible to hope that the radiological phosphene (the X-ray phosphene) may serve as a test for the determination of the individual radiational excitability of the central nervous system.


Nitrate Nervous System Central Nervous System Azide Experimental System 
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  1. 1.
    Ts. M. Avakyan and V. A. Tumanyan, “Toward a theory of the visibility of X-rays,”Izv. AN ArmSSR,9, No. 8, 21–24 (1956).Google Scholar
  2. 2.
    A. I. Bogoslovskii, V. K. Zhdanov, and G. V. Mildazhene, “The nature of oscillator potentials in the ERG of man and their functional significance,” in:The Mechanisms of the Operation of Receptor Elements of the Sense Organs [in Russian], Leningrad (1973), pp. 10–15.Google Scholar
  3. 3.
    V. Glavaty, Z. Dienstvir, and M. Zhak, “Possibility of determining the reaction of the organism to irradiation in small doses of infrared radiation by means of observation of the phosphene threshold of the retina,”Med. Radiologiya,8, No. 11, 47–50 (1963).Google Scholar
  4. 4.
    R. Granit,The Electrophysiological Investigation of Reception [in Russian], Moscow (1957).Google Scholar
  5. 5.
    G. K. Gurtovoi and E. O. Burdyanskaya, “Visual sensations induced by X-ray radiation of the eye with doses of the order of a milliroentgen,”Biofizika,4, No. 6, 708–713 (1960).Google Scholar
  6. 6.
    M. A. Ostrovskii, “Photoreception,” in:The Physiology of Sensory Systems. Part 1. The Physiology of Vision [in Russian], Leningrad (1971), pp. 1–101.Google Scholar
  7. 7.
    B. N. Savchenko,The Comparative Characteristics of the Net Electroretinogram Induced by Light and X-ray Stimulation [in Russian], Leningrad (1977).Google Scholar
  8. 8.
    J. E. Dowling, Quoted in [6].Google Scholar
  9. 9.
    L. E. Lipetz, “Electrophysiology of the X-ray phosphene,”Rad. Res.,2, 306–329 (1955).Google Scholar
  10. 10.
    M. A. Murakami and G. Kaneko, Quoted in [6].Google Scholar
  11. 11.
    W. K. Noell, “The effect of iodoacetate on the vertebrate retina,”J. Cell. Comp. Physiol.,37, 283–308 (1951).Google Scholar
  12. 12.
    W. K. Noell,Studies on the Electrophysiology and the Metabolism of the Retina, Texas (1953).Google Scholar
  13. 13.
    W. K. Noell, “The impairment of visual cell structure by iodoacetate,”J. Cell. Comp. Physiol.,40, 25–55 (1955).Google Scholar
  14. 14.
    J. C. Peskin, “The effect of irradiation upon visual purple,”Amer. J. Ophthalm.,39, No. 6, 849–854 (1955).Google Scholar
  15. 15.
    D. D. Polis and J. Wyeth, Quoted in [2].Google Scholar
  16. 16.
    T. G. Smith, W. K. Stell, and J. E. Brown, Quoted in [6].Google Scholar
  17. 17.
    L. Wachtmeister, “Luminosity functions of the oscillatory potential of the human electroretinogram,”Acta Ophthalmol.,52, No. 3, 353–366 (1974).Google Scholar
  18. 18.
    L. Wachtmeister, “Incremental thresholds of the oscillatory potentials of the human electroretinogram in response to coloured light,”Acta Ophthalmol.,52, No. 3, 378–389 (1974).Google Scholar

Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • B. N. Savchenko
    • 1
  1. 1.Department of the Human and Animal PhysiologyState UniversityLeningrad

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