Neuroscience and Behavioral Physiology

, Volume 10, Issue 3, pp 227–231 | Cite as

Effect of steroids with antiandrogenic properties on androgenic and myotrophic activity of testosterone and some of its derivatives

  • T. I. Ivanenko
Article
Received:

Conclusions

  1. 1.

    17,17-Dimethyl-18-norandrostadien-4,13-one-3 had an inhibitory effect on the mass of the accessory sexual glands and m. levator ani in castrated sexually immature male rats, which is stimulated by testosterone and its structural analogs — preparations of anabolic activity, when administered for 7 days.

     
  2. 2.

    The antihormonal effects of the antiandrogen investigated depended on the dose and agonist used.

     
  3. 3.

    It was shown that our modified method (a single administration of a long-acting anabolic with 7-day administration of an antiandrogen) can be used to evaluate the biological properties of preparations capable of decreasing the androgenic effects of anabolic steroids.

     

Keywords

Steroid Testosterone Biological Property Structural Analog Anabolic Steroid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • T. I. Ivanenko
    • 1
  1. 1.Laboratory of Biological Standardization of Hormones, Institute of Experimental Endocrinology and Hormone ChemistryAcademy of Medical Sciences of the USSRMoscow

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