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The in vitro fertilization program in Helsinki

  • Aarne I. Koskimies
  • Anssi Tenhunen
  • Pekka Ylöstalo
  • Sirkka Liukkonen
  • Olof Widholm
  • Markku Seppäla
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Summary

In the in vitro fertilization program at Departments I and II of Gynecology and Obstetrics, University of Helsinki, 57 patients were stimulated with clomiphene and hMG. Follicular growth was monitored by ultrasound and serum estradiol measurements. Laparoscopic follicular puncture was performed 36h after hCG injection. Three hundred seventy-five follicles were punctured and 227 oocytes recovered, representing an oocyte recovery rate of 61%. A total of 130 oocytes (57%) showed evidence of fertilization and 71% of the fertilized oocytes cleaved. Fifty-seven embryo transfers were carried out at the two-to eight-cell stage. Multiple embryos were transferred to 24 patients. Biochemical pregnancies were encountered in two cases; early abortions, 3–5 weeks after implantation, in two cases. One normal ongoing single pregnancy occurred from a transfer of three four-cell embryos.

Keywords

Public Health Estradiol Developmental Biology Recovery Rate Embryo Transfer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Edwards RG, Bavister BD, Steptoe PC: Early stages of fertilization in vitro of human oocytes matured in vitro. Nature 1969;221:632–635PubMedGoogle Scholar
  2. 2.
    Renou P, Trounson A, Wood C, Leeton JF: Collection of mature oocytes for in vitro fertilization. Fertil Steril 1981;35:409–412PubMedGoogle Scholar
  3. 3.
    Trounson A, Leeton JF, Wood C, Webb J, Wood J: Successful human pregnancies byin vitro fertilization and embryo transfer in the controlled ovulatory cycle. Science 1981;212:681–682Google Scholar

Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Aarne I. Koskimies
    • 1
  • Anssi Tenhunen
    • 1
  • Pekka Ylöstalo
    • 1
  • Sirkka Liukkonen
    • 1
  • Olof Widholm
    • 1
  • Markku Seppäla
    • 1
  1. 1.Departments I and II of Obstetrics and GynecologyUniversity Central Hospital of HelsinkiHelsinki 29Finland

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