Origins of life

, Volume 6, Issue 3, pp 413–421 | Cite as

Primary catalytic systems of biogenesis and structure-functional evolution of biocatalysers

  • G. Georgiev
  • N. Bakardjieva


An important aspect of biological evolution is the development of biocatalyzers. The connection between abiotic and biological catalyzers is discussed, and the role of metal ions as primary catalysts is considered. The evolutionary demand for greater specificity and efficiency may have been fulfilled through the formation of metal-organic complexes and later through enzyme systems. Metal ions are probably responsible for the formation of some of the isoenzymes found in contemporary organisms.


Enzyme Organic Chemistry Geochemistry Enzyme System Catalytic System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Anokhin, P. K.: 1968,Systems Theory and Biology, Springer-Verlag, p. 376.Google Scholar
  2. Anokhin, P. K.: 1948,Bull. Eksperim. Biol. i Med. 26, 81.Google Scholar
  3. Bakardjieva, N.: 1966,Compt. Rend. Acad. Bulg. Sci. 19, 1067.Google Scholar
  4. Bakardjieva, N. and Jordanov, N.: 1967,Compt. Rend. Acad. Bulg. Sci. 20, 591.Google Scholar
  5. Bakardjieva, N.: 1968,Compt. Rend. Acad. Bulg. Sci. 21, 1113.Google Scholar
  6. Bakardjieva, N.: 1970,Compt. Rend. Acad. Bulg. Sci. 23, 591.Google Scholar
  7. Bakardjieva, N.: 1971,Compt. Rend. Acad. Bulg. Sci. 24, 671.Google Scholar
  8. Bakardjieva, N.: 1971,Compt. Rend. Acad. Bulg. Sci. 24, 1411.Google Scholar
  9. Bakardjieva, N.: 1972,Spisanie na Bulg. Akad. Naukite 5, 20.Google Scholar
  10. Bernal, J.: 1965,The Origins of Prebiological Systems and of Their Molecular Matrices, Acad. Press, New York.Google Scholar
  11. Ben-Hayyim, G. and Avron, M.: 1970,Biochim. Biophys. Acta 205, 86.Google Scholar
  12. Boitchenko, E. A.: 1971,Chem. Evolution and the Origin of Life, North-Hall, Publ. Comp., pp. 453–457.Google Scholar
  13. Boitchenko, E. A.: 1971,J. Evoluz. Biochimii i Fiziol. 7, 447.Google Scholar
  14. Boitchenko, E. A.: 1973,J. Evoluz. Biochim. i. Fiziol. 9, 14.Google Scholar
  15. Boitchenko, E. A.: 1968,Uspehi Sovrem. Biol. 66, 173.Google Scholar
  16. Bowen, H. J. M.: 1966,Trace Elements in Biochemistry, Acad. Press, New York.Google Scholar
  17. Calvin, M.: 1969,Chemical Evolution, Clarendon Press, Oxford.Google Scholar
  18. Cennamo, C.: 1967,Ital. J. Biochem. 16, 3.Google Scholar
  19. Conclin, M. E. and Smith, H.: 1971,Amer. J. Bot. 58, 688.Google Scholar
  20. Dobry-Duclaux, A. and May, A.: 1968,Bull. Soc. Chim. Biol. 50, 2053.Google Scholar
  21. Erkama, J.: 1950,Trace Elements in Plant Physiology, Lotsya, p. 53.Google Scholar
  22. Gaffron, H.: 1960, in F. Steward (ed.),Plant Physiology, London, N.Y.Google Scholar
  23. Georgiev, G. and Bakardjieva, N.: 1973,Compt. Rend. Acad. Bulg. Sci. 26, in press.Google Scholar
  24. Hewitt, E.: 1958,Encycl. of Plant Physiol. 4.Google Scholar
  25. Hewitt, E. J. and Nicholas, D. J. D.: 1963,Metabolic Inhibitors 2, 311.Google Scholar
  26. Ilin, V. S., Pleskov, V. N., and Razumovskaja, N. I.: 1967,J. Evol. Bioch. Physiol. 3, 519.Google Scholar
  27. Kaplan, N. O.: 1963,Bacteriol. Rev. 27, 155.Google Scholar
  28. Kobashi, K.: 1968,Biochem. Biophys. Acta 158, 239.Google Scholar
  29. Kornberg, A., Ochoa, S., and Mehler, A.: 1946,J. Biol. Chem. 17, 159.Google Scholar
  30. Krebs, H. A.: 1942,Biochem. J. 36, 33.Google Scholar
  31. Lamden, M. P. and Kunin, A. S.: 1970,FEBS Letters 11, 328.Google Scholar
  32. Malmström, B. G.: 1969, 6 Meeting FEBS, Madrid, Abstracts volume.Google Scholar
  33. Markert, C. L. and Whitt, G. S.: 1968,Experientia 24, 977.Google Scholar
  34. Markert, C. L. and Möller, F.: 1959,Proc. Nat. Acad. Sci. U. S. A. 45, 753.Google Scholar
  35. Mengel, K.: 1964,Ernährung und Stoffwechsel der Pflanze, G. Fischer Verlag, Jena, 1964.Google Scholar
  36. Mildvan, A. S.: 1970,Enzymes 2, 446.Google Scholar
  37. Monod, J., Wyman, J., and Changeux, J.: 1965,J. Molec. Biol. 12, 88.Google Scholar
  38. Morita, Y., Yoshida, Ch., Kitamura, I., and Ida, Sh.: 1970,Agr. Biol. Chem. 34, 1191.Google Scholar
  39. Nason, A.: 1958,Soil Sci. 85, 63.Google Scholar
  40. Newsholme, E. A.: 1965,Sci. Progr. 53, 237.Google Scholar
  41. Ogata, J., Kosugi, Y., and Mormoto, T.: 1968,Tetrahedron 24, 4057.Google Scholar
  42. Pilet, P. E. and Gaspor, Th.: 1968,Le catabolisme auxinuque, 1968.Google Scholar
  43. Shannon, L. M.: 1968,Ann. Rev. Plant Physiol. 19, 187.Google Scholar
  44. Stadtman, E. R.: 1970,Enzymes 1, 398.Google Scholar
  45. Stafford, H. A. and Bravinder-Bree, S.: 1972,Plant Physiol. 49, 950.Google Scholar
  46. Siegel, B. Z. and Galston, A. W.: 1967,Plant Physiol. 42, 221.Google Scholar
  47. Stiles, W.: 1958,Encyclopedia of Plant Physiology,4, Springer Verlag.Google Scholar
  48. Suleimanov, I. G., Ramazanova, L. H., and Alekseeva, V. J.: 1970.Google Scholar
  49. Szent-Györgyi, H.: 1939,Naturwissenschaften 27, 95.Google Scholar
  50. Thatcher, B. W.: 1934,Science 79, 463.Google Scholar
  51. Tchernavina, I. A.: 1970,Fisiologia i Biochimija Mikroelementov, Moskwa.Google Scholar
  52. Trubachev, I. N.: 1968,Fisiol. Rastenii 15, 658.Google Scholar
  53. Udelnova, T. M.: 1969, ‘Soedinenija marganza v rasteniah i ih vozmojnoe utchastie v reakziah photosintesa’, Avtoreferat disertazii. Moskva.Google Scholar
  54. Ullman, A. and Monod, J.: 1969,Biochim. Biophys. Res. Commun. 35, 35.Google Scholar
  55. Upitis, V. V., Pakalne, D. S., and Nollendorf, A. F.: 1971,Mikroelementi, Riga.Google Scholar
  56. Vallee, B. S. and Coleman, J. E.: 1964, in M. Florkin (ed.),Comprehensive Biochemistry, Vol. 12, Elsevier.Google Scholar
  57. Vallee, B. L. and Williams, R. J. P.: 1968,Proc. Nat. Acad. Sci. U. S. A. 59, 498.Google Scholar
  58. Yakovleva, V. I.: 1968,Uspehi Biol. Himii 9, 55.Google Scholar
  59. Yamashita, K., Itoh, M., and Shibata, K.: 1969,Biochim. Biophys. Acta 189, 133.Google Scholar
  60. Zlatarov, A.: 1934,God. Na Sof. Univ. 1934.Google Scholar

Copyright information

© D. Reidel Publishing Company 1975

Authors and Affiliations

  • G. Georgiev
    • 1
  • N. Bakardjieva
    • 2
  1. 1.Dept. of Plant Physiol.Sofia State Univ.SofiaBulgaria
  2. 2.Inst. of Plant Physiol.Bulg. Acad. Sci.SofiaBulgaria

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