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The Hemizona Assay (HZA): Finding sperm that have the “right stuff”

  • Gary D. Hodgen
  • Lani J. Burkman
  • Charles C. Coddington
  • Daniel R. Franken
  • Sergio C. Oehninger
  • Thinus F. Kruger
  • Zev Rosenwaks
Editorials

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References

  1. 1.
    Burkman LJ, Coddington CC, Franken DR, Kruger T, Rosenwaks Z, Hodgen GD: The hemizona assay (HZA): Development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential. Fertil Steril 1988:49:688–697Google Scholar
  2. 2.
    Overstreet JW, Yanagimachi R, Katz DR, Hayashi K, Hanson FW: Penetration of human spermatozoa into the human zona pellucida and the zona-free hamster egg: A study of fertile donors and infertile patients. Fertil Steril 1980:33:534–542Google Scholar
  3. 3.
    Franken DR, Burkman LJ, Oehninger SC, Coddington CC, Veeck LL, Kruger TF, Rosenwaks Z, Hodgen GD: The hemizona assay using salt stored human oocytes: Evaluation of zona pelludica capacity for binding human spermatozoa. Gamete Res 1988 (in press)Google Scholar
  4. 4.
    Yanagimachi R, Lopata A, Odom CB, Bronson RA, Mahi CA, Nicolson GL: Retention of biologic characteristics of zona pellucida in highly concentrated salt solution: The use of salt-stored eggs for assessing the fertilizing capacity of spermatozoa. Fertil Steril 1979:31:562–574Google Scholar
  5. 5.
    Franken DR, Oehninger SC, Burkman LJ, Coddington CC, Kruger TF, Rosenwaks Z, Acosta AA, Hodgen GD: The hemizona assay (HZA): A predictor of human sperm fertilizing potential in IVF treatment J Vitro Fert Embryo Transfer 1988 (in press)Google Scholar
  6. 6.
    WHO: WHO Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction. New York, Cambridge University Press, 1987Google Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Gary D. Hodgen
    • 1
  • Lani J. Burkman
    • 1
  • Charles C. Coddington
    • 1
    • 2
  • Daniel R. Franken
    • 1
    • 3
  • Sergio C. Oehninger
    • 1
  • Thinus F. Kruger
    • 4
  • Zev Rosenwaks
    • 1
  1. 1.The Jones Institute for Reproductive medicine, Department of Obstetrics and GynecologyEastern Virginia Medical SchoolNorfolk
  2. 2.Portsmouth Naval HospitalPortsmouth
  3. 3.Department of Obstetrics and GynecologyUniversity of the Orange Free StateBloemfonteinRepublic of South Africa
  4. 4.Department of Obstetrics and GynecologyUniversity of Stellenbosch, Tygerberg HospitalTygerbergRepublic of South Africa

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