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More homologies among the vertebrate plasma proteins

Abstract

Many of the proteins of vertebrate blood plasma share common ancestry. As more sequences are reported, the network of relationships continues to expand in unexpected directions. Computer analysis now reveals that a minor plasma protein of unknown function, gamma-trace protein, is related to the kininogen family. Some other possible relationships have been uncovered also, including a resemblance between the histidine-rich hinge regions of high molecular weight kininogen and hemopexin and between Factor VIII and Von Willebrand Factor.

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References

  1. Barnett DR, Lee TH & Bowman BH (1972) Biochemistry11, 1189–1194.

  2. Cole T, Inglis AS, Roxburgh CM, Howlett GJ & Schreiber G (1985) FEBS Lett.182, 57–61.

  3. Dayhoff MO (1978)Atlas of Protein Sequence and Structure, vol 5, suppl 3, National Biomedical Research Foundation, Washington, D.C.

  4. Doolittle RF (1981) Science214, 149–159.

  5. Doolittle RF (1983) Science222, 417–419.

  6. Doolittle RF (1984) in:The Plasma Proteins (Putnam FW, ed) pp 317–360, Academic Press, New York.

  7. Doolittle RF (1985) Trends in Biochemical Sciences10, 233–237.

  8. Esnard F and Gauthier F (1983) J. Biol. Chem.258, 12443–12447.

  9. Feng DF, Johnson MS & Doolittle RF (1985) J. Mol. Evol.21, 112–125.

  10. Fitch WM (1966) J. Mol. Biol.16, 9–16.

  11. Ginsburg D, Handin RI, Bonthron DT, Donlon TA, Bruns GAP, Latt SA & Orkin SH (1985) Science228, 1401–1406.

  12. Grubb A & Lofberg H (1982) Proc. Natl. Acad. Sci. U.S.A.79, 3024–3027.

  13. Hill RL, Delaney R, Fellows RE Jr & Lebovitz HE (1966) Proc. Natl. Acad. Sci. U.S.A.56, 1762–1765.

  14. Iwanaga S, Kato H, Ikari N, Hashimoto N & Fujii S (1979) in:Biological Functions of Proteinases (Holzer H & Tschesche H, eds), pp 245–259, Springer-Verlag, Heidelberg.

  15. Nawa H, Kitamura N, Hirose T, Asai M, Inayama S & Nakanishi S (1983) Proc. Natl. Acad. Sci. U.S.A.80, 90–94.

  16. Needleman SB and Wunsch CD (1970) J. Mol. Biol.48, 443–453.

  17. Reid KBM & Porter RR (1981) Ann. Rev. Biochem.50, 433–464.

  18. Reid KBM & Thompson EOP (1978) Biochem. J.173, 863–868.

  19. Singer SJ & Doolittle RF (1966) Science153, 13–25.

  20. Sottrup-Jensen L, Stepanic TM, Kristensen T, Lonblad PB, Jones PB, Wierzbicki DM, Magnusson S, Domdey H, Wetsel RA, Lundwall A, Tack BF and Fey GH (1985) Proc. Natl. Acad. Sci. U.S.A.82, 9–13.

  21. Takahashi N, Takahashi Y and Putnam FW (1985) Proc. Natl. Acad. Sci. U.S.A.82, 73–77.

  22. Tanaka T, Ohkubo H and Nakanishi S (1984) J. Biol. Chem.259, 8063–8065.

  23. Toole JJ, Knopf JL, Wozney JM, Sultzman LA, Buecker JL, Pittman DD, Kaufman RJ, Brown E, Shoemaker C, Orr EC, Amphlett GW, Foster WB, Coe ML, Knutson GJ Fas DN & Hewick RM (1984) Nature312, 342–346.

  24. Vehar GA, Keyt B, Eaton D, Rodriquez H, O'Brien DP, Rotblat F, Opperman H, Keck R, Wood WL, Hargens RN, Tuddenham EGD, Lawn RM & Capon DJ (1984) Nature312, 337–342.

  25. Yang F, Brune JL, Naylor SL, Copples RL, Naberhaus KH & Bowman BH (1985) Proc. Natl. Acad. Sci. U.S.A., in press.

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Doolittle, R.F. More homologies among the vertebrate plasma proteins. Biosci Rep 5, 877–884 (1985). https://doi.org/10.1007/BF01119899

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Keywords

  • Molecular Weight
  • High Molecular Weight
  • Plasma Protein
  • Unknown Function
  • Blood Plasma