, Volume 131, Issue 1, pp 9–12

A case of cutaneous phaeohyphomycosis caused byExserohilum rostratum, its in vitro sensitivity and review of literature

  • Abha Agarwal
  • S. M. Singh
Human And Animal Mycology


A 40 year old woman presented with the infection of skin of 3 years duration on the upper anterior aspect of fore-arm. Histologic examination of the skin tissue revealed dematiaceous hyphae, aggregated structures or single celled elements. On detailed mycological examination the isolate was identified asExserohilum rostratum. Among the antimycotic tested in vitro amorolfine was found to be most effective with MIC value of 3 mcg/ml. This is the first report ofE. rostratum infection of man from India.

Key words

Cutaneous phaeohyphomycosis Exserohilum rostratum 


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  1. 1.
    Alcorn JL. Generic concepts inDrechslera, Bipolaris andExserohilum. Mycotaxon 1983; 17: 1–86.Google Scholar
  2. 2.
    Fuste FJ, Ajello L, Threkeld A, Henry JE, Jr.Drechslera hawaiiensis causative agent of a fatal fungal meningoencephalitis. Sabouraudia 1973; 11: 59–63.Google Scholar
  3. 3.
    Young CN, Swart JG, Acermann D, Davigepitts K. Nasal obstruction and bone erosion caused byDrechslera hawaiiensis. J. Laryngol Otol. 1978; 92: 137–143.Google Scholar
  4. 4.
    Rolston KVI, Hopfer RL, Lorson DL. Infection caused byDrechslera species, case report and review of the literature. Review Infect. Dis 1985; 7: 525–529.Google Scholar
  5. 5.
    Yoshimori RN, Moore RA, Itabashi HH, Fujikawa DG. Phaeohyphomycosis of brain: granulomatous encephalitis, caused byDrechslera specifera. Am. J. Clin. Pathol 1982; 77: 363–370.Google Scholar
  6. 6.
    Zapater RC, Albesi EJ, Garcia GH, Mycotic keratitis byDrechslera specifera. Sabouraudia 1975; 13: 295–298.Google Scholar
  7. 7.
    Ajello L, Iger M, Wybel Rand Uigil FJ.Drechslera rostrata as an agent of phaeohyphomycosis. Mycologia 1980: 72: 1094–1102.Google Scholar
  8. 8.
    Bridges CH, Beasley JN. Maduromycotic mycetomas in animals —Brachycladium speciferum Bainier as an etiologic agent. J. Am. Vet. Med. Assoc. 1960; 137: 192–201.Google Scholar
  9. 9.
    Muller GH, Kaplan W, Ajello L, Padhye AA. Phaeohyphomycosis caused byDrechslera spicifera in a cat. J. Am. Vet. Med. Assoc. 1975; 166: 150–154.Google Scholar
  10. 10.
    Kwochka KW, Mayer MBC, Ajello L, Padhye AA. Canine phaeohyphomycosis caused byDrechslera spicifera, a case report and literature review. J. Am. Hosp. Assoc. 1983; 2: 625–633.Google Scholar
  11. 11.
    Hall JE, Multiple maduromycotic mycetomas in a colt caused byHelminthosporium. South West Vet. 1965; 18: 233–234.Google Scholar
  12. 12.
    Kaplan W, Chandler FW, Ajello L, Ganthier, R, Higgins R, Cayouetle P. Equine phaeohyphomycosis caused byDrechslera specifera. Can. Vet. J. 1975; 16: 205–208.Google Scholar
  13. 13.
    Schauffle AF. Maduromycotic mycetoma in an aged mare. J. Am. Vet. Assoc. 1972; 160: 998–1000.Google Scholar
  14. 14.
    Davis CL, Shorten HL. Granulomatous nasalswelling in a bovine. J. Am. Vet. Med. Assoc. 1936; 89: 91–96.Google Scholar
  15. 15.
    McKenzie RA, Cannole D. Mycotic nasal granuloma in cattle. Aust. Vet. J. 1977; 53: 268–270.Google Scholar
  16. 16.
    Patton.Helminthosporium spiciforum as the cause of dermal and nasal maduromycosis in cow. Cornell Vet. 1977: 67: 236–244.Google Scholar
  17. 17.
    Pritchard D, Chick BF, Cannole MD. Eumycotic mycetoma due toDrechslera rostrata infection in a cow. Aust. Vet. J. 1977; 53: 241–244.Google Scholar
  18. 18.
    Rayner RW. A Mycological colour chart. Commonwealth Mycological Institute, Kew, 1970.Google Scholar
  19. 19.
    Emmons CW, Binford CH, Utz JP, Kwon-Chung KJ. Medical Mycology. Philadelphia, Lea and Febiger. Third edition. 1977; pp. 190, 200, 486, 559.Google Scholar
  20. 20.
    Polak A. Antifungal activity. ‘In vitro’ of Ro 14-4767/002. A phenylpropylmorpholine. Sabouraudia 1983; 21: 205–213.Google Scholar
  21. 21.
    Adam RD, Paquin ML, Petersen E. Saubolle MA, Rinaldi MG, Corcoran JG, Galgiani JN, Sobonya RE. Phaeohyphomycosis caused by the fungal generaBipolaris andExserohilum. Medicine 1986; 65: 203–217.Google Scholar
  22. 22.
    Douer D, Gold Schmied-Reouven A, Segev S, Ben Bassat I. HumanExserohilum andBipolaris, infections, report ofExserohilum nasal infection in a neutropenic patient with acute leukemia. Vet. Mycology 1987; 25: 235–241.Google Scholar
  23. 23.
    Forster RK, Rebell G, Wilson LA. Dematiaceous fungal keratitis — Clinical isolates and management. Br. J. Ophthalmol 1975; 59: 372–376.Google Scholar
  24. 24.
    McGinnis MR, Rinaldi MG, Winn RE. Emerging agents of phaeohyphomycosis: Pathogenic species ofBipolaris andExserohilum. J. Clin. Micro. 1986; 24: 250–259.Google Scholar
  25. 25.
    Padhye AA, Ajello L, Wieden MA, Steinbronn KK. Phaeohyphomycosis of the nasal sinuses caused by a new species ofExserohilum. J. of Clin. Micro. 1986; 24: 245–249.Google Scholar
  26. 26.
    Drouhet E, Dupont B. Laboratory and Clinical assessment of ketoconazole in deep seated mycoses. Am. J. of Med. 1983; 74 (Suppl. 1B): 30–47.Google Scholar

Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Abha Agarwal
    • 1
  • S. M. Singh
    • 1
  1. 1.Medical Microbiology Laboratory, Department of Biological SciencesRani Durgavati UniversityJabalpurIndia

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