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Polyserositis in a patient with acute paracoccidioidomycosis and hepatosplenic schistosomiasis

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A severe case of juvenile paracoccidioidomycosis (PCM), manifested as cholestatic jaundice, lymphnode enlargement and an unusual form of polyserositis, associated with portal hypertension secondary to schistosomiasis, as well as bactermias caused byE. coli andS. aureus and post-transfusional hepatitis C is reported. Temporary unresponsiveness of in vivo and in vitro cellular immune responses toP. brasiliensis were registered. The authors discuss the possible interference of either agent in the host immune response, thus explaining the severity of PCM in the present case.

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Correspondence to Dra. M. A. Shikanai-Yasuda.

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Shikanai-Yasuda, M.A., Benard, G., Duarte, M.I.S. et al. Polyserositis in a patient with acute paracoccidioidomycosis and hepatosplenic schistosomiasis. Mycopathologia 130, 75–78 (1995). https://doi.org/10.1007/BF01103453

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Key words

  • Immunodeficiency
  • P. brasiliensis
  • Paracoccidioidomycosis
  • Polyserositis
  • Schistosomiasis