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Morphometric studies of dense-cored vesicles in Type I cells of rat carotid body

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Summary

Two subclasses of Type I cells of rat carotid body were recognized by analyzing the diameters of dense-cored vesicles. One group of cells contained vesicles with a mean diameter of about 52 nm; in the other group of cells the vesicles measured about 71 nm. The mean volume of the small vesicle cell (SVC) was roughly 3/4 that of the large vesicle cell (LVC). Furthermore there were significant differences between SVC and LVC in volume densities of vesicles (0.4 versus 0.9%), mitochondria (14 versus 17%) and nuclei (49 versus 38%).

The fingerlike extensions typical of the Type I cells were more common for LVC than for SVC. The majority of the nerve-endings observed terminated on LVC.

The significance of these differences has yet to be determined.

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Hellström, S. Morphometric studies of dense-cored vesicles in Type I cells of rat carotid body. J Neurocytol 4, 77–86 (1975). https://doi.org/10.1007/BF01099097

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Keywords

  • Volume Density
  • Carotid Body
  • Small Vesicle
  • Large Vesicle
  • Morphometric Study