Biochemical response in rats to the addition of curry leaf (Murraya koenigii) and mustard seeds (Brassica juncea) to the diet
- 88 Downloads
Three groups with 12 weanling male albino rats were group fed for 90 days on a standard laboratory rat diet plus 20% coconut oil either without a supplement or with the addition of 10% curry leaf or 10% mustard seeds. Feed was offered at a level of 10% body weight. At the end of the trial, measurements were made on the total serum cholesterol, high density lipoproteins, low density lipoproteins, and very low density lipoproteins fractions, release of lipoproteins into the circulation, lecithin cholesterol acyl transferase activity and lipoprotein lipase activity. Feed intake and mean body weight of the rats on each treatment was not significantly different. Both spices resulted in a reduction in total serum cholesterol and LDL+VLDL, an increase in the HDL, lower release of lipoproteins into the circulation and an increase in the LCAT activity.
Key wordsCurry leaf Mustard Spices Lecithin cholesterol acyl transferase Lipoproteins Cholesterol
Unable to display preview. Download preview PDF.
- 2.Sharma RD, Raghuram TC (1991) Hypolipidaemic effect of fenugreek seeds: A clinical study. Phyt Ther Res 30: 145–147.Google Scholar
- 4.Abraham A, Kurup PA (1988) Mechanism of hypercholesterolemia produced by biotin deficiency. J Biosci 12: 187.Google Scholar
- 5.Sreenivasan MR, Chandrasekhara N (1992) Effect of mangoginger on lipid status in normal and hypertriglyceridemic rats. J Food Sci Tech 29: 130–131.Google Scholar
- 6.Sreenivasan MR, Satyanarayana MN (1988) Influence of capsaicin, eugenol, curcumin and ferulic acid on sucrose induced hypertriglyceridemia in rats. Nutr Rep Int 38: 571–579.Google Scholar
- 8.Frederickson DS, Levy RI, Leis RS (1976) Fat transport in lipoprotein: An integrated approach to mechanism and disorders. N Engl J Med 276: 32.Google Scholar
- 10.Miller NE, Relle DS, Forden OH (1977). High density lipoproteins as a protective care control study. Lancet 1977 (i): 965.Google Scholar
- 12.Sambaiah K, Satyanarayana MN, Rao MVL (1978) Effect of red pepper and capsaicin on fat absorption and liver fat in rats. Nutr Rep Int 18: 521–525.Google Scholar
- 13.Gujral S, Bhumra N, Swaroop M (1978) Effect of ginger oleoresin on serum and hepatic cholesterol levels in cholesterol fed rats. Nutr Rep Int 17: 183.Google Scholar
- 14.Sambaiah K, Satyanarayana MN (1982) Influence of red pepper and capsaicin on body composition and lipogenesis in rats. J Bio Sci 4: 425.Google Scholar