Tetramethylsuccinonitrile in polyvinyl chloride products for food and its release into food-simulating solvents

  • Hajimu Ishiwata
  • Takiko Inoue
  • Kunitoshi Yoshihira
Original Papers


The content of tetramethylsuccinonitrile (TMSN), the main decomposition product of 2,2′-azobis-isobutyronitrile, in polyvinyl chloride (PVC) products used for food packaging, were examined as well as food-simulating solvents. The TMSN concentration in 17 PVC products ranged from below the detection limit, 0.05 mg/kg, up to 523 mg/kg. The release of TMSN from two PVC products into five kinds of food-simulating solvents at 60 °C for 30 min was observed, except for 1 ± 1 μg/kg of TMSN in n-heptane from a PVC bottle containing 523±30.4 mg/kg of TMSN. The detection limit of TMSN in the food-simulating solvents was 1 μg/kg. When pieces of the bottle were stored in olive oil at 40 °C for 120 days, 5 ± 1 μg/kg of TMSN was detected in the oil. The release of TMSN from the pieces of the bottle into olive oil between 80 and 140 °C depended on the formula 1ny = 0.08786x - 5.696,r = 0.9927, wherey is the concentration (μg/kg) of TMSN in olive oil, x is the temperature (°C), andr is the correlation coefficient.


Polyvinyl Chloride Food Packaging Main Decomposition Chloride Product Main Decomposition Product 
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Tetramethyl-succinonitril in Polyvinylchloridprodukten für Lebensmittel und seine Freisetzung in simulierenden Lösungsmitteln


Untersucht wurde der Gehalt von Tetramethyl-Succinonitril (TMSN), dem Hauptzersetzungsprodukt von 2,2′-Azobis-iso-butyronitril, in Polyvinylchloridprodukten (PVC) für Lebensmittel im Zusammenhang mit dessen Freisetzung in simulierenden Lösungsmitteln. Die TMSN-Konzentration in 17 PVC-Produkten lag teilweise unterhalb der Meßgrenze; ansonsten lag sie zwischen 0,05 und 523 mg/kg. Ausgenommen von 1 ± 1 μg/kg TMSN in n-Heptan aus einer PVC-Flasche, die 523 ± 30,4 mg/kg, TMSN enthielt, wurde bei einer Temperatur von 60 °C innerhalb von 30 min aus zwei PVC-Produkten keine Freisetzung von TMSN in fünf verschiedenen simulierenden Lösungsmitteln beobachtet. Die Erfassungsgrenze von TMSN in den simulierenden Lösungsmitteln lag bei 1 μg/kg. Bei Aufbewahrung von Teilen der PVC-Flasche in Olivenöl bei 40 °C für 120 Tage wurden 5 ± 1 μg/kg TMSN im Olivenöl erfaßt. Die Freisetzung von TMSN aus der Flasche in das Olivenöl bei Temperaturen zwischen 80 und 140 °C verlief nach der Formel Iny = 0,08786x - 5,696, (r = 0,9927);y = Konzentration (μg/kg von TMSN im Olivenöl),x = Temperatur (°C) undr = Korrelationskoeffizient.


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • Hajimu Ishiwata
    • 1
  • Takiko Inoue
    • 1
  • Kunitoshi Yoshihira
    • 1
  1. 1.National Institute of Hygienic SciencesSetagaya-ku, TokyoJapan

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