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The American Journal of Digestive Diseases

, Volume 22, Issue 6, pp 477–484 | Cite as

Adrenocorticosteroid therapy in alcoholic hepatitis

A prospective, double-blind randomized study
  • Bennett L. Blitzer
  • Milton G. Mutchnick
  • Prakash H. Joshi
  • Michael M. Phillips
  • J. Michael Fessel
  • Harold O. Conn
Original Articles

Abstract

In a prospective, randomized, double-blind study of prednisolone therapy of acute alcoholic hepatitis, 39% of the total group of 28 patients died. Mortality and cumulative survival were similar in steroid- and placebo-treated patients. After 14 days of therapy, the serum albumin concentration and white blood count were significantly higher in the steroid group, but all other parameters were similar. An increased risk of fungal infection appeared to be associated with steroid therapy.

Keywords

Public Health Steroid Hepatitis Albumin Serum Albumin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Digestive Disease Systems, Inc. 1977

Authors and Affiliations

  • Bennett L. Blitzer
    • 1
    • 2
  • Milton G. Mutchnick
    • 1
    • 2
  • Prakash H. Joshi
    • 1
    • 2
  • Michael M. Phillips
    • 1
    • 2
  • J. Michael Fessel
    • 1
    • 2
  • Harold O. Conn
    • 1
    • 2
  1. 1.Medical ServiceVeterans Administration HospitalWest Haven
  2. 2.Department of Internal MedicineYale University School of MedicineNew Haven

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